SCHEMBL623198

SCHEMBL623198

NC(=O)C(=O)c1cccc(C(N)=O)c1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
METAP2 P50579 1/20 0.42
GAA P10253 1/20 0.41
G6PD P11413 1/20 0.41
CASP7 P55210 1/20 0.41
CASP6 P55212 1/20 0.41
BCAT2 O15382 1/20 0.41
PARP1 P09874 5/20 0.41
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
PDPK1 O15530 1/20 0.40
AURKA O14965 2/20 0.38
PLK4 O00444 1/20 0.38
CHEK1 O14757 1/20 0.38
DAPK3 O43293 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40536 0.89 ALDH1A1 (0.54) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL7780248 0.80 G6PD (0.63) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL6999515 0.78 KDM4E (0.45) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL998313 0.77 MMP2 (0.48) ALDH1A1KDM4EMAPTHPGDTSHR
Hydrochloric Acid SCHEMBL631451 0.76 MMP2 (0.47) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL2020740 0.76 G6PD (0.69) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL624771 0.75 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDHSD17B10METAP2
SCHEMBL160221 0.74 CES2 (0.48) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL158431 0.74 CD44 (0.48) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL161850 0.74 METAP2 (0.47) ALDH1A1KDM4EMAPTHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012020483-A1 3-AMINOOXALYL AMINOBENZAMIDE DERIVATIVE, AND INSECTICIDE AND MITICIDE USING SAME AS ACTIVE INGREDIENT アグロカネショウ株式会社 (JP) 2012-02-16 WO disclosed