Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607240 | 0.80 | DRD2 (0.48) | MCHR1DRD2DRD4S1PR5ALDH1A1 | |
| SCHEMBL6251149 | 0.80 | DRD4 (0.50) | MCHR1KMT2ADRD2DRD4HTT | |
| SCHEMBL6231994 | 0.79 | ALDH1A1 (0.47) | MCHR1DRD2DRD4HTTKDM4E | |
| SCHEMBL6235676 | 0.78 | CA2 (0.50) | MCHR1HTTSMN1; SMN2KDM4E | |
| SCHEMBL6231136 | 0.77 | LMNA (0.50) | MCHR1DRD2DRD4S1PR5KDM4E | |
| SCHEMBL6231990 | 0.74 | HRH4 (0.48) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL5764654 | 0.73 | MCHR1 (0.49) | MCHR1MEN1KMT2ADRD2DRD4 | |
| SCHEMBL3153917 | 0.73 | MEN1 (0.74) | MEN1KMT2ADRD2DRD4SLC18A3 | |
| SCHEMBL16113630 | 0.72 | OGA (0.58) | MEN1KMT2ADRD2DRD4OGA | |
| Hydrochloric Acid SCHEMBL16113438 | 0.71 | OGA (0.57) | MEN1KMT2ADRD2DRD4OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |