SCHEMBL6234487

SCHEMBL6234487

O=C(Cl)Oc1cccc(OC(=O)Cl)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ACMSD Q8TDX5 1/20 0.41
ALDH1A1 P00352 7/20 0.39
POLB P06746 1/20 0.36
LMNA P02545 2/20 0.36
METAP2 P50579 1/20 0.36
METAP1 P53582 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
MAPT P10636 3/20 0.34
KMT2A Q03164 1/20 0.34
MAPK8 P45983 1/20 0.33
HSD17B10 Q99714 1/20 0.33
F2 P00734 1/20 0.33
F10 P00742 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772213 0.86 HTR7 (0.41) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL377165 0.80 KDM4E (0.44) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL9207095 0.80 MAPT (0.50) KDM4ETSHRALDH1A1MAPTKMT2A
SCHEMBL10768300 0.76 MEN1 (0.52) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL2518688 0.76 KDM4E (0.46) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL29944969 0.76 CES2 (0.43) KDM4ETDP1TSHRALDH1A1POLB
SCHEMBL2523378 0.76 CES2 (0.43) KDM4ETDP1TSHRALDH1A1POLB
SCHEMBL9033949 0.76 MGAM (0.47) KDM4ETSHRALDH1A1LMNAMAPT
SCHEMBL1732930 0.74 L3MBTL1 (0.45) KDM4ETDP1ALOX15TSHRACMSD
SCHEMBL9565278 0.74 PLAAT3 (0.34) KDM4ETDP1ALDH1A1POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1196452-B8 METHOD FOR COPOLYMERIZING POLAR AND NON-POLAR MONOMERS LANXESS DEUTSCHLAND GMBH (DE) 2005-08-03 EP disclosed
EP-1196452-B1 METHOD FOR COPOLYMERIZING POLAR AND NON-POLAR MONOMERS BAYER AG (DE) 2005-06-08 EP disclosed
EP-1196452-A1 METHOD FOR COPOLYMERIZING POLAR AND NON-POLAR MONOMERS Bayer Aktiengesellschaft (DE) 2002-04-17 EP disclosed
WO-2001000686-A1 METHOD FOR COPOLYMERIZING POLAR AND NON-POLAR MONOMERS BAYER AKTIENGESELLSCHAFT (DE) 2001-01-04 WO disclosed
EP-1044992-A1 Catalytic system for the polymerisation of olefin Bayer Aktiengesellschaft (DE) 2000-10-18 EP disclosed