Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | PNMT | P11086 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200716 | 0.85 | PNMT (0.58) | SIRT2ADRA2APNMTKIF11TDP2 | |
| SCHEMBL27408384 | 0.84 | PNMT (0.54) | SIRT2ADRA2APNMTKIF11TDP2 | |
| SCHEMBL16972804 | 0.84 | PDE3B (0.53) | SIRT2ADRA2APNMTKIF11TDP2 | |
| Methane SCHEMBL27508397 | 0.84 | PNMT (0.57) | SIRT2ADRA2APNMTKIF11TDP2 | |
| Ammonia Solution, Strong SCHEMBL28209706 | 0.84 | PNMT (0.57) | SIRT2ADRA2APNMTKIF11TDP2 | |
| SCHEMBL516986 | 0.80 | KIF11 (0.67) | SIRT2ADRA2APNMTKIF11TDP2 | |
| Sulfuric Acid SCHEMBL29269875 | 0.79 | PNMT (0.51) | SIRT2ADRA2APNMTTDP2CAPN9 | |
| Butane SCHEMBL27459660 | 0.79 | PNMT (0.51) | SIRT2ADRA2APNMTTDP2MAPT | |
| Acetaldehyde SCHEMBL27415337 | 0.79 | PNMT (0.51) | SIRT2ADRA2APNMTTDP2MAPT | |
| Pyrimidine SCHEMBL28303381 | 0.78 | ADRA2A (0.50) | SIRT2ADRA2APNMTKIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277630-A1 | Antibacterial agents | CHUPAK LOUIS S | 2005-12-15 | — | — | US | disclosed |
| EP-1594495-A1 | OXAZOLIDINONE DERIVATES N-SUBSTITUTED BY A TRICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069245-A1 | OXAZOLIDINONE DERIVATES N-SUBSTITUTED BY A TRICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277630-A1 | Antibacterial agents | MRPL21, RPN2, FBL | SIRT2 1558/4885ADRA2A 3793/4885PNMT 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.