SCHEMBL6234856

SCHEMBL6234856

O=C(CO)NC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712181 0.76 ALDH1A1 (0.44) L3MBTL1ALDH1A1TP53TSHR
SCHEMBL26628356 0.74 CYP1A2 (0.39) L3MBTL1ALDH1A1
SCHEMBL2373214 0.73
SCHEMBL31734135 0.71 ALDH1A1 (0.39) L3MBTL1ALDH1A1TP53TSHR
SCHEMBL6969487 0.69 ALDH1A1 (0.37) L3MBTL1ALDH1A1TP53TSHR
SCHEMBL3136565 0.69 ALDH1A1 (0.44) L3MBTL1ALDH1A1TP53TSHR
SCHEMBL28207990 0.67 OR51E2 (0.30)
SCHEMBL1563693 0.67 CRBN (0.41) L3MBTL1ALDH1A1TP53TSHR
SCHEMBL4948924 0.67
SCHEMBL7937203 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107709343-B Vaccine against streptococcus pneumoniae serotype 5 马克斯·普朗克科学促进学会 2021-05-18 CN disclosed
EP-3303357-B1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 5 MAX PLANCK GESELLSCHAFT (DE) 2021-05-12 EP disclosed
US-10596272-B2 Vaccines against Streptococcus pneumoniae serotype 5 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-03-24 US disclosed
US-20180296687-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 5 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2018-10-18 US disclosed
EP-3303357-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 5 Max-Planck-Gesellschaft zur Förderung der Wissenschaften (DE) 2018-04-11 EP disclosed
CN-107709343-A Vaccine against Streptococcus pneumoniae serotype 5 马克斯·普朗克科学促进学会 2018-02-16 CN disclosed
WO-2016198170-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 5 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-12-15 WO disclosed
EP-0865283-A4 2-DEOXYSTREPTAMINE AS A MOLECULAR SCAFFOLD FOR PREPARING FUNCTIONALLY AND SPACIALLY DIVERSE MOLECULES AND PHARMACEUTICAL COMPOSITIONS THEREOF ANADYS PHARMACEUTICALS INC (US) 2005-07-20 EP disclosed
US-6140361-A FOR INHIBITING BINDING OF HUMAN IMMUNODEFICIENCY VIRUS REV PROTEIN TO REV RESPONSIVE ELEMENTS (RRE) SCRIPTGEN PHARMACEUTICALS, INC. (US) 2000-10-31 US disclosed
US-5942547-A FOR INHIBITING BINDING OF HUMAN IMMUNODEFICIENCY VIRUS PROTEIN TO RESPONSIVE ELEMENT; TREATMENT OF AIDS SCRIPTGEN PHARMACEUTICALS, INC. (US) 1999-08-24 US disclosed
EP-0865283-A1 2-DEOXYSTREPTAMINE AS A MOLECULAR SCAFFOLD FOR PREPARING FUNCTIONALLY AND SPACIALLY DIVERSE MOLECULES AND PHARMACEUTICAL COMPOSITIONS THEREOF Scriptgen Pharmaceuticals Inc. (US) 1998-09-23 EP disclosed
WO-1997009053-A9 2-DEOXYSTREPTAMINE AS A MOLECULAR SCAFFOLD FOR PREPARING FUNCTIONALLY AND SPATIALLY DIVERSE MOLECULES AND PHARMACEUTICAL COMPOSITIONS THEREOF 1997-05-01 WO disclosed
WO-1997009053-A1 2-DEOXYSTREPTAMINE AS A MOLECULAR SCAFFOLD FOR PREPARING FUNCTIONALLY AND SPATIALLY DIVERSE MOLECULES AND PHARMACEUTICAL COMPOSITIONS THEREOF SCRIPTGEN PHARMACEUTICALS, INC. (US) 1997-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180296687-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 5 FUT5, SPAG5, IL5 L3MBTL1 3234/4885ALDH1A1 3515/4885TP53 953/4885
US-10596272-B2 Vaccines against Streptococcus pneumoniae serotype 5 FUT5, SPAG5, IL5 L3MBTL1 3234/4885ALDH1A1 3515/4885TP53 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.