Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238639 | 0.78 | ALDH1A1 (0.36) | IDO1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2093905 | 0.71 | RAB9A (0.38) | IDO1NPC1RAB9ATAAR1ALDH1A1 | |
| SCHEMBL9561133 | 0.70 | NPC1 (0.45) | IDO1NPC1RAB9ATAAR1KMT2A | |
| SCHEMBL6235370 | 0.70 | IDO1 (0.42) | IDO1TAAR1KMT2AMEN1KDM4E | |
| SCHEMBL3301625 | 0.70 | TAAR1 (0.59) | IDO1TAAR1ARKDM4EALDH1A1 | |
| SCHEMBL6002379 | 0.67 | SLC6A3 (0.41) | TAAR1ARDAOSMN1; SMN2 | |
| SCHEMBL4806763 | 0.66 | — | — | |
| SCHEMBL28654144 | 0.66 | ALDH1A1 (0.59) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL2091553 | 0.64 | ALDH1A1 (0.46) | IDO1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL2095762 | 0.64 | LTA4H (0.39) | IDO1NPC1RAB9ATAAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |