Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044323 | 0.90 | SMYD3 (0.33) | SMYD3F2GPR132GCKFKBP1A | |
| SCHEMBL4040540 | 0.83 | CTSK (0.51) | SMYD3CTSVCTSLCTSSCTSK | |
| SCHEMBL4043646 | 0.83 | CTSS (0.38) | SMYD3CTSVCTSLCTSSCTSK | |
| SCHEMBL4045303 | 0.82 | CTSK (0.37) | SMYD3CTSLCTSSCTSKALDH1A1 | |
| SCHEMBL4045954 | 0.82 | SMYD3 (0.33) | SMYD3CTSSCTSKALDH1A1FKBP1A | |
| SCHEMBL4044199 | 0.82 | SMYD3 (0.34) | SMYD3F2ALDH1A1FKBP1AF10 | |
| SCHEMBL6238658 | 0.81 | HSD17B10 (0.37) | SMYD3CTSKALDH1A1GAA | |
| SCHEMBL4042255 | 0.81 | CTSS (0.42) | CTSVCTSLCTSSCTSKGPR132 | |
| SCHEMBL4045457 | 0.80 | FKBP1A (0.39) | SMYD3ALDH1A1FKBP1A | |
| SCHEMBL4051011 | 0.80 | HCRTR2 (0.34) | SMYD3CTSVCTSLCTSSGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |