Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775896 | 0.88 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AGPR132SMN1; SMN2 | |
| SCHEMBL8775748 | 0.79 | ALOX5 (0.63) | ALDH1A1HTT | |
| SCHEMBL8775835 | 0.78 | MAOA (0.43) | ALDH1A1HTTKMT2AMAOBSMN1; SMN2 | |
| SCHEMBL9005549 | 0.76 | SRD5A2 (0.63) | KMT2ANPC1RAB9ASRD5A2 | |
| SCHEMBL8775947 | 0.75 | MAPK1 (0.47) | HTTGPR132SMN1; SMN2 | |
| SCHEMBL28178916 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL8775912 | 0.73 | CA12 (0.41) | HTTGPR132SMN1; SMN2 | |
| SCHEMBL6236504 | 0.73 | NAPRT (0.51) | SMN1; SMN2SRD5A2 | |
| SCHEMBL2494140 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HTTKMT2ASMN1; SMN2SRD5A2 | |
| SCHEMBL4957778 | 0.70 | MAOB (0.50) | ALDH1A1MEN1KMT2AMAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |