Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775912 | 0.89 | CA12 (0.41) | LMNAALOX5HTTSMN1; SMN2 | |
| SCHEMBL6236504 | 0.81 | NAPRT (0.51) | MMP1MMP2MMP9MMP13F2 | |
| SCHEMBL8775748 | 0.74 | ALOX5 (0.63) | ALOX5ALDH1A1HTTKCNA5 | |
| SCHEMBL8775926 | 0.74 | NR3C2 (0.44) | LMNAPSMB5HTTKCNA5TBXAS1 | |
| SCHEMBL8775765 | 0.70 | ROCK2 (0.48) | LMNAALDH1A1HTTGAATSHR | |
| SCHEMBL27687109 | 0.70 | SMN1; SMN2 (0.50) | LMNAFAAHALDH1A1HTTKCNA5 | |
| SCHEMBL8775861 | 0.70 | TBXAS1 (0.56) | LMNAALOX5ALDH1A1HTTKCNA5 | |
| SCHEMBL6037547 | 0.69 | ALOX5 (0.56) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9299750 | 0.69 | FFAR1 (0.43) | ALOX5GAATSHR | |
| SCHEMBL8775928 | 0.69 | TBXAS1 (0.60) | LMNAALOX5HTTKCNA5TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807626-A1 | N-HYDROXYUREA DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1997-11-19 | — | — | EP | disclosed |