Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.49 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264146 | 0.83 | ALDH1A1 (0.52) | ADORA2AADORA2BKDRMERTKNPY5R | |
| SCHEMBL17220082 | 0.76 | LMNA (0.50) | ADORA2AKDRMERTK | |
| SCHEMBL6237020 | 0.76 | TDP1 (0.58) | ADORA2AADORA2BCTSKCTSLCTSS | |
| SCHEMBL14264134 | 0.75 | ALDH1A1 (0.71) | NPY5RMEN1KMT2A | |
| SCHEMBL14264133 | 0.75 | ALDH1A1 (0.66) | NPY5RMEN1KMT2A | |
| SCHEMBL29664801 | 0.73 | ALDH1A1 (0.49) | ADORA2ACTSKMEN1KMT2A | |
| SCHEMBL6235242 | 0.73 | CTSK (0.76) | ADORA2ACTSKMEN1KMT2A | |
| SCHEMBL9480610 | 0.72 | RAB9A (0.61) | KDRMERTKNPY5RMEN1KMT2A | |
| SCHEMBL10099686 | 0.72 | KCNH3 (0.77) | ADORA2AADORA2BMERTKNPY5RMEN1 | |
| SCHEMBL10073747 | 0.72 | KCNH3 (0.77) | ADORA2AADORA2BMERTKNPY5RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |