SCHEMBL6237284

SCHEMBL6237284

CCc1nn(-c2ccccc2)c(=O)c2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
MAPK1 P28482 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
ALOX15 P16050 1/20 0.59
BCAT1 P54687 1/20 0.54
GAA P10253 3/20 0.50
NPSR1 Q6W5P4 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KHK P50053 2/20 0.48
ADORA3 P0DMS8 3/20 0.48
PDE4A P27815 1/20 0.47
PDE4B Q07343 1/20 0.47
PDE4C Q08493 1/20 0.47
PDE4D Q08499 1/20 0.47
MAPT P10636 1/20 0.47
AURKA O14965 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7587368 0.85 BCAT1 (0.55) ALDH1A1MAPK1L3MBTL1BCAT1GAA
SCHEMBL8372488 0.79 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1GAAKHK
SCHEMBL12203808 0.77 SMN1; SMN2 (0.61) ALDH1A1L3MBTL1ALOX15GAAHTT
SCHEMBL14917566 0.77 RAB9A (0.76) ALDH1A1MAPK1L3MBTL1BCAT1GAA
SCHEMBL24076967 0.74 ALOX15 (1.00) ALDH1A1L3MBTL1ALOX15GAANPSR1
SCHEMBL4060721 0.74 BCAT1 (0.58) ALDH1A1MAPK1BCAT1GAANPSR1
SCHEMBL9231347 0.72 NPSR1 (0.79) ALDH1A1MAPK1L3MBTL1ALOX15BCAT1
SCHEMBL30719634 0.72 NPSR1 (0.79) ALDH1A1MAPK1L3MBTL1ALOX15BCAT1
SCHEMBL14518042 0.72 ALDH1A1 (0.59) ALDH1A1MAPK1BCAT1NPSR1HTT
SCHEMBL22552352 0.70 DHODH (0.62) ALDH1A1MAPK1L3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1072614-B1 Method for polymerizing vinyl monomers in a coated reactor SHINETSU CHEMICAL CO (JP) 2005-07-06 EP disclosed
EP-0934955-B1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHINETSU CHEMICAL CO (JP) 2003-04-16 EP disclosed
US-6362291-B1 PRETREATING VESSEL HAS ANTIDEPOSIT COATING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-26 US disclosed
US-6335403-B1 ANTISCALING AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-01 US disclosed
US-6320001-B1 COATING INNER WALL SURFACES WITH A POLYMER SCALE PREVENTIVE FILM OF AN AROMATIC OR HETEROCYCLIC COMPOUND HAVING 5 OR MORE CONJUGATED PI BONDS DYE AND/OR PIGMENT ON THE FIRST LAYER AND A SECOND LAYER OF A DYE AND/OR PIGMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-11-20 US disclosed
EP-1072614-A1 Method for polymerizing vinyl monomers in a coated reactor SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-01-31 EP disclosed
EP-1063242-A1 Process for producing a polymer by polymerization of a monomer having an ethylenic double bond SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-12-27 EP disclosed
EP-1043338-A1 Polymerisation process in a reactor with double coating against scale formation SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-10-11 EP disclosed
US-6037426-A POLYMERIZING MONOMER HAVING ETHYLENIC DOUBLE BOND IN POLYMERIZATION VESSEL HAVING BILAYER POLYMER SCALE PREVENTIVE COATING FILM ON INNER WALL SURFACES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-03-14 US disclosed
EP-0934955-A1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-08-11 EP disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed