Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31295589 | 1.00 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAGLAHPGD | |
| Hydrochloric Acid SCHEMBL15486584 | 0.98 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL3884423 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL1354320 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EGAAGLAHPGD | |
| SCHEMBL98371 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EGAAHPGDHTT | |
| SCHEMBL6014732 | 0.83 | PARP10 (0.53) | ALDH1A1KDM4EGAAHTTTSHR | |
| Hydrochloric Acid SCHEMBL25217998 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL570110 | 0.83 | GAA (0.61) | ALDH1A1KDM4EGAAGLAHPGD | |
| Hydrochloric Acid SCHEMBL31095289 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EGAAHTTLMNA | |
| SCHEMBL2190365 | 0.82 | ACHE (0.59) | ALDH1A1HTTTSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12281057-B2 | Carboxamides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-04-22 | — | — | US | disclosed |
| EP-3651752-B1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-11-20 | — | — | EP | disclosed |
| US-20230286907-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-09-14 | — | — | US | disclosed |
| US-11603351-B2 | Carboxamides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-03-14 | — | — | US | disclosed |
| US-20210094906-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED | 2021-04-01 | — | — | US | disclosed |
| US-20200368232-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | INNOVATION PHARMACEUTICALS INC. (US) | 2020-11-26 | — | — | US | disclosed |
| EP-3651752-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2020-05-20 | — | — | EP | disclosed |
| US-10647661-B2 | Carboxamides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-05-12 | — | — | US | disclosed |
| CN-111065383-A | Carboxamides useful as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2020-04-24 | — | — | CN | disclosed |
| EP-2811993-B1 | METHODS OF TREATING FIBROSIS | NOGRA PHARMA LTD (IE) | 2019-10-09 | — | — | EP | disclosed |
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011121555-A1 | ANTIBACTERIAL ISOQUINOLIN-3-YLUREA DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011084970-A1 | ANTI-HEPARIN COMPOUNDS | POLYMEDIX INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20110098498-A1 | Processes For Preparing A Polymeric Compound | POLYMEDIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| US-20110098498-A1 | Processes For Preparing A Polymeric Compound | POLYMEDIX, INC. (US) | 2011-04-28 | — | — | US | disclosed |
| WO-2011050162-A1 | PROCESSES FOR PREPARING A POLYMERIC COMPOUND | POLYMEDIX, INC. (US) | 2011-04-28 | — | — | WO | disclosed |
| EP-2010482-A1 | COUPLING COMPOUNDS AND HAIR DYEING COMPOSITIONS CONTAINING THEM | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007118817-A1 | COUPLING COMPOUNDS AND HAIR DYEING COMPOSITIONS CONTAINING THEM | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-10-25 | — | — | WO | disclosed |
| EP-1847528-A1 | Coupling compounds and hair dyeing compositions containing them | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2007-10-24 | — | — | EP | disclosed |
| US-4054661-A | Pyridyl oxamic acid derivatives and use in the prevention of allergic reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200368232-A1 | Host Defense Protein (HDP) Mimetics For Prophylaxis And/Or Treatment Of Inflammatory Diseases Of The Gastrointestinal Tract | FABP2, HMGB1, MASP2 | ALDH1A1 4257/4885KDM4E 4676/4885GAA 2688/4885 |
| US-20110098498-A1 | Processes For Preparing A Polymeric Compound | F12, ALG1, ABCB11 | ALDH1A1 1028/4885KDM4E 2276/4885GAA 294/4885 |
| US-11603351-B2 | Carboxamides as modulators of sodium channels | TRPV1, SCN2A, SCN10A | ALDH1A1 2665/4885KDM4E 1582/4885GAA 2969/4885 |
| US-20210094906-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | TRPV1, SCN2A, SCN10A | ALDH1A1 2665/4885KDM4E 1582/4885GAA 2969/4885 |
| US-10647661-B2 | Carboxamides as modulators of sodium channels | TRPV1, SCN2A, SCN10A | ALDH1A1 2665/4885KDM4E 1582/4885GAA 2969/4885 |
| US-20230286907-A1 | CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | TRPV1, SCN2A, SCN10A | ALDH1A1 2665/4885KDM4E 1582/4885GAA 2969/4885 |
| US-12281057-B2 | Carboxamides as modulators of sodium channels | TRPV1, SCN2A, SCN10A | ALDH1A1 2665/4885KDM4E 1582/4885GAA 2969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.