SCHEMBL6238752

SCHEMBL6238752

C=C[Si](N(C)C(C)=O)(N(C)C(C)=O)N(C)C(C)=O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202575 0.77 ALDH1A1 (0.35) ALDH1A1
SCHEMBL9635607 0.77 ALDH1A1 (0.35) ALDH1A1
SCHEMBL7608983 0.70
SCHEMBL508215 0.70 LMNA (0.36) ALDH1A1
SCHEMBL11124444 0.69
SCHEMBL29009685 0.67 ALDH1A1 (0.36) ALDH1A1
SCHEMBL449837 0.65 CHRM1 (0.35) ALDH1A1
SCHEMBL537585 0.65
SCHEMBL611009 0.64
Ethylene SCHEMBL6684740 0.63 ALDH1A1 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375096-B Synthesis method of amido silane 江西晨光新材料股份有限公司 2023-05-02 CN disclosed
WO-2005028486-A1 METHODS OF REFINING SILANE COMPOUNDS HONEYWELL INTERNATIONAL INC. (US) 2005-03-31 WO disclosed
US-20050059835-A1 Methods of refining silane compounds HONEYWELL INTERNATIONAL INC. (US) 2005-03-17 US disclosed
EP-0739652-B1 Method for the continuous production of room-temperature-curable organopolysiloxane compositions DOW CORNING TORAY SILICONE (JP) 2001-05-30 EP disclosed
EP-1008613-A2 Process for preparing room temperature vulcanizing silicone compositions DOW CORNING CORPORATION (US) 2000-06-14 EP disclosed
US-6008290-A A ROOM TEMPERATURE-CURABLE ORGANOPOLYSILOXANE HAVING HYDROXYL OR HYDROLYZABLE END GROUPS, A MONO-, DI- OR TRIKETOXIMESILANE AND A TETRAKETOXIMESILANE AND A TRIAZOLE-CONTAINING COMPOUND, E.G. TEBUCONAZOLE; ADHESIVES; SEALS; DISCOLORATION INHIBITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-12-28 US disclosed
US-5861460-A MIXING POLYSILOXANE WITH AN ORGANOSILANE HAVING TWO SILICON-BONDED HYDROLYZABLE GROUPS, POWDERED INORGANIC FILLER AND CURE-ACCELERATING CATALYST, THEN VACUUM DEGASSING YIELDS STRONG, DURABLE CURED POLYSILOXANES; EFFICIENCY DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-01-19 US disclosed
EP-0586184-B1 Polydimethylsiloxanes for modulus reduction and method for their preparation DOW CORNING (US) 1997-10-01 EP disclosed
EP-0562878-B1 Room temperature curable organopolysiloxane composition and cured product of the same SHINETSU CHEMICAL CO (JP) 1997-05-14 EP disclosed
EP-0739652-A1 Method for the continuous production of room-temperature-curable organopolysiloxane compositions Dow Corning Toray Silicone Company Limited (JP) 1996-10-30 EP disclosed
US-5236997-A Curable fluorosilicone rubber composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-08-17 US disclosed
EP-0337478-B1 CONCRETE JOINT SEALANT HAVING IMPROVED ADHESION DOW CORNING CORPORATION (US) 1992-07-15 EP disclosed
US-5093454-A Moisture and hot water-resistant adhesives and seals TOSHIBA SILICONE CO., LTD. (JP) 1992-03-03 US disclosed
US-5039736-A Hydroxy-terminated polysiloxane, surface treated hydrophobic silica filler, hexamethyldisilazane, hydrolyzable organosilane compound; good mold releasability SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-08-13 US disclosed
US-5015413-A Primers with good coating properties and storage stability TOSHIBA SILICONE CO., LTD. (JP) 1991-05-14 US disclosed
EP-0337478-A2 Concrete joint sealant having improved adhesion DOW CORNING CORPORATION (US) 1989-10-18 EP disclosed
EP-0337791-A2 Self leveling highway sealant DOW CORNING CORPORATION (US) 1989-10-18 EP disclosed
US-4810748-A MOISTURE CURABLE SILICONE ELASTOMERS DOW CORNING CORPORATION (US) 1989-03-07 US disclosed
US-4579636-A BLEND OF POLYSILOXANE, VINYL TRIALKOXYSILANE AND MERCAPTOPOLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-04-01 US disclosed
US-4302571-A TERMINATED AT BOTH ENDS WITH SILANOIC HYDROXY GROUPS AND AN ORGANOSILANE OR ORGANOPOLYSILOXANE WITH HYDROLYZABLE GROUPS TO SERVE AS CROSSLINKING AGENTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 1981-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059835-A1 Methods of refining silane compounds HDAC10, HDAC1, HDAC11 ALDH1A1 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.