Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241857 | 0.81 | KEAP1 (0.42) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5724902 | 0.81 | PTGIR (0.38) | ALDH1A1MAPT | |
| SCHEMBL6239956 | 0.79 | HTT (0.42) | MEN1KMT2AKDM4EMAPTMMP2 | |
| SCHEMBL15559295 | 0.78 | CES2 (0.41) | OGG1KDM4EMAPTHDAC3HDAC4 | |
| SCHEMBL25638233 | 0.78 | ALDH1A1 (0.43) | KMT2AKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29523783 | 0.75 | OGG1 (0.35) | OGG1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17161281 | 0.74 | ALOX5 (0.44) | OGG1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL21767229 | 0.73 | OGG1 (0.48) | OGG1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9795712 | 0.73 | KEAP1 (0.40) | OGG1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL11247372 | 0.73 | MAPT (0.41) | OGG1MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005002574-A1 | PYRAZOLIDINEDIONE DERIVATIVES AND THEIR USE AS PLATELET AGGREGATION INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2005-01-13 | — | — | WO | disclosed |