Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624218 | 0.84 | KCNMA1 (0.53) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL623943 | 0.82 | MEN1 (0.51) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL625028 | 0.81 | DYRK1A (0.52) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL625901 | 0.81 | NPC1 (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL625958 | 0.80 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL10083543 | 0.80 | MCHR1 (0.47) | MCHR1GAA | |
| SCHEMBL10083554 | 0.78 | KMT2A (0.44) | ALDH1A1LMNAKMT2AMAPTMCHR1 | |
| SCHEMBL10083535 | 0.78 | DDX3X (0.49) | KMT2AMEN1MAPTMCHR1 | |
| SCHEMBL624357 | 0.78 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1LMNAKMT2A | |
| SCHEMBL625180 | 0.77 | ADORA3 (0.53) | SMN1; SMN2ALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |