Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 7/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10084313 | 0.80 | MEN1 (0.34) | NTRK1MAPTPOLBABL1EGFR | |
| SCHEMBL624210 | 0.79 | MAPK8 (0.39) | CAMK2DHDAC3HDAC1MAPTPOLB | |
| SCHEMBL624357 | 0.71 | RAB9A (0.51) | HDAC3HDAC1MAPTPOLBLMNA | |
| SCHEMBL10083553 | 0.70 | KDM4E (0.51) | POLBABL1EGFRSRCALDH1A1 | |
| SCHEMBL13974535 | 0.70 | ADORA2A (0.49) | KDM1AALDH1A1HPGDMAPK14FYN | |
| SCHEMBL2850317 | 0.69 | KDM1A (0.58) | KDM1AHDAC3HDAC1NTRK1MAPT | |
| SCHEMBL623932 | 0.69 | RAB9A (0.59) | MAPTPOLBALDH1A1HTT | |
| SCHEMBL623924 | 0.68 | ABL1 (0.56) | MAPTABL1EGFRSRCALDH1A1 | |
| SCHEMBL623623 | 0.67 | KDR (0.53) | HDAC3HDAC1MAPTPOLBABL1 | |
| SCHEMBL625959 | 0.67 | HDAC6 (0.46) | HDAC3HDAC1POLBABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |