Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10083553 | 0.74 | KDM4E (0.51) | GAAEGFRABL1SRCSMN1; SMN2 | |
| SCHEMBL623623 | 0.73 | KDR (0.53) | HDAC6NPC1RAB9AEGFRABL1 | |
| SCHEMBL627181 | 0.73 | ROCK2 (0.54) | NPC1RAB9ACSNK1DCSNK2A1 | |
| SCHEMBL623932 | 0.72 | RAB9A (0.59) | NPC1RAB9AGAASMN1; SMN2POLB | |
| SCHEMBL23566353 | 0.72 | SCD (0.63) | HDAC6SCDNPC1RAB9AGAA | |
| SCHEMBL21858360 | 0.71 | RAB9A (0.61) | SCDNPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL624357 | 0.71 | RAB9A (0.51) | NPC1RAB9AGAASMN1; SMN2HDAC3 | |
| SCHEMBL623924 | 0.70 | ABL1 (0.56) | EGFRABL1SRCALDH1A1BCR | |
| SCHEMBL625756 | 0.69 | CHRM4 (0.52) | NPC1RAB9AGAAABL1SMN1; SMN2 | |
| SCHEMBL625899 | 0.69 | MAPT (0.46) | NPC1RAB9AGAASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |