Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624209 | 0.79 | CAMK2D (0.41) | HDAC3HDAC1ALDH1A1LMNAMAPT | |
| SCHEMBL624357 | 0.73 | RAB9A (0.51) | HDAC3HDAC1KMT2AMEN1KDM4E | |
| SCHEMBL19440879 | 0.72 | KMT2A (0.51) | HDAC3HDAC1KMT2AMEN1KDM4E | |
| SCHEMBL627181 | 0.71 | ROCK2 (0.54) | CLK2DYRK1AMAPK1 | |
| SCHEMBL623932 | 0.70 | RAB9A (0.59) | KMT2AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL10083553 | 0.70 | KDM4E (0.51) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL19442552 | 0.68 | KMT2A (0.49) | HDAC3HDAC1KMT2AMEN1KDM4E | |
| SCHEMBL623924 | 0.68 | ABL1 (0.56) | ALDH1A1MAPTMAPK1CHEK1CDK7 | |
| SCHEMBL569981 | 0.68 | L3MBTL1 (0.43) | MAPK8HDAC3KMT2AMEN1KDM4E | |
| SCHEMBL623623 | 0.67 | KDR (0.53) | HDAC3HDAC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |