SCHEMBL624324

SCHEMBL624324

CC(O)N(CCCCN(c1ccc(N)cc1)C(C)O)c1ccc(N)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.41
TDP1 Q9NUW8 4/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
PSMD14 O00487 1/20 0.41
TSHR P16473 1/20 0.41
RECQL P46063 1/20 0.41
GFER P55789 1/20 0.41
ALOX15 P16050 2/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 3/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PHLPP2 Q6ZVD8 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6723886 0.92 ALDH1A1 (0.48) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
SCHEMBL526297 0.82 TDP1 (0.52) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
SCHEMBL9856682 0.82 TDP1 (0.52) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
SCHEMBL9437910 0.81 TDP1 (0.41) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
SCHEMBL2032767 0.78 TDP1 (0.38) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
SCHEMBL8414086 0.76 MAPT (0.49) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
SCHEMBL21784092 0.76 ALDH1A1 (0.43) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
Sulfuric Acid SCHEMBL8625325 0.75 ALDH1A1 (0.44) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1
SCHEMBL4358312 0.74 KCNH2 (0.36) ALDH1A1L3MBTL1TSHRTP53MAPT
SCHEMBL11787205 0.73 KMT2A (0.37) L3MBTL1MAPTKMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6537328-B1 Hair dye L'OREAL S.A. (FR) 2003-03-25 US claimed
EP-4362906-A1 COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE L'OREAL (FR) 2024-05-08 EP disclosed
EP-4362889-A1 COMPOSITION COMPRISING AT LEAST ONE OXIDATION DYE, 1,3-PROPANEDIOL, AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE FATTY SUBSTANCE L'OREAL (FR) 2024-05-08 EP disclosed
EP-4362891-A1 COMPOSITION COMPRISING AT LEAST ONE PARTICULAR COUPLER, AT LEAST ONE PARTICULAR OXIDATION BASE, AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ANIONIC POLYSACCHARIDE L'OREAL (FR) 2024-05-08 EP disclosed
WO-2023275187-A1 COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275193-A1 COMPOSITION COMPRISING AT LEAST ONE OXIDATION DYE, 1,3-PROPANEDIOL, AT LEAST ONE ALKALINE AGENT AND AT LEAST ONE FATTY SUBSTANCE L'OREAL (FR) 2023-01-05 WO disclosed
WO-2023275168-A1 COMPOSITION COMPRISING AT LEAST ONE PARTICULAR COUPLER, AT LEAST ONE PARTICULAR OXIDATION BASE, AT LEAST ONE FATTY SUBSTANCE AND AT LEAST ONE ANIONIC POLYSACCHARIDE L'OREAL (FR) 2023-01-05 WO disclosed
WO-2021138257-A1 COMPOSITIONS FOR IMPARTING COLOR AND TONE TO THE HAIR SHI MINLI (US) 2021-07-08 WO disclosed
EP-3731801-A1 COMPOSITIONS FOR ALTERING THE COLOR OF HAIR L'OREAL (FR) 2020-11-04 EP disclosed
EP-3694485-A1 SPECIFIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINES, METHOD, AND COMPOSITION L'OREAL (FR) 2020-08-19 EP disclosed
US-7223294-B2 Composition for the oxidation dyeing of keratin fibres, comprising a polyoxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty alcohol L'OREAL (FR) 2007-05-29 US disclosed
US-7204859-B2 Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides L'OREAL S.A. (FR) 2007-04-17 US disclosed
US-7115147-B2 Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated carboxylic acid ether, a mono- or polyglycerolated surfactant and a nonionic oxyalkylenated surfactant L'OREAL (FR) 2006-10-03 US disclosed
US-20060156477-A1 Symmetrical diazo compounds comprising 2-imidazolium groups and a non-cationic linke, compositions comprising them, method of coloring, and device L'OREAL S.A. (FR) 2006-07-20 US disclosed
US-20040172771-A1 Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides L'OREAL S.A. (FR) 2004-09-09 US disclosed
US-6692539-B2 Cationic or amphoteric polymer whose cationic charge density is greater than or equal to 2 meq/gram. L'OREAL (FR) 2004-02-17 US disclosed
US-20030229948-A1 Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated caboxylic acid ether, a mono-or polyglycerolated surfactant and a nonionic oxyalkylenated surfactant L'OREAL (FR) 2003-12-18 US disclosed
US-20030192134-A1 Composition for the oxidation dyeing of keratin fibres, comprising a polyoxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty alcohol L'OREAL (FR) 2003-10-16 US disclosed
US-20030172473-A1 Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer L'OREAL (FR) 2003-09-18 US disclosed
US-20030172475-A1 Composition useful for the oxidation dyeing of keratin fibres, containing a polyoxyalkylenated carboxylic acid ether, a mono-or polyglycerolated surfactant and an unsaturated fatty alcohol L'OREAL (FR) 2003-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040172771-A1 Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides KRT18, FASN, ADH1A CYP3A4 710/4885TDP1 4053/4885ALDH1A1 45/4885
US-20030192134-A1 Composition for the oxidation dyeing of keratin fibres, comprising a polyoxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty alcohol KRT18, ELOVL5, FASN CYP3A4 1040/4885TDP1 4468/4885ALDH1A1 175/4885
US-20030172473-A1 Composition useful for the oxidation dyeing of keratin fibres, containing an oxyalkylenated carboxylic acid ether, a nonionic surfactant and a particular polymer KRT18, KRTCAP2, CUTA CYP3A4 2088/4885TDP1 3533/4885ALDH1A1 1206/4885
US-20060156477-A1 Symmetrical diazo compounds comprising 2-imidazolium groups and a non-cationic linke, compositions comprising them, method of coloring, and device KRT18, NR2E3, NOX5 CYP3A4 1058/4885TDP1 3690/4885ALDH1A1 2851/4885
US-20030172475-A1 Composition useful for the oxidation dyeing of keratin fibres, containing a polyoxyalkylenated carboxylic acid ether, a mono-or polyglycerolated surfactant and an unsaturated fatty alcohol KRT18, HACD3, ELOVL5 CYP3A4 2421/4885TDP1 4465/4885ALDH1A1 587/4885
US-20030229948-A1 Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated caboxylic acid ether, a mono-or polyglycerolated surfactant and a nonionic oxyalkylenated surfactant KRT18, KRTCAP2, PLOD2 CYP3A4 2697/4885TDP1 4385/4885ALDH1A1 1301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.