Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259212 | 0.73 | ADRB2 (0.57) | ADRB1ADRB2 | |
| SCHEMBL6248506 | 0.68 | ADRA2A (0.30) | ADRB2 | |
| SCHEMBL28535211 | 0.66 | ADRA2A (0.62) | ADRB1ADRB2MEN1MAPTKMT2A | |
| SCHEMBL9768276 | 0.64 | ADRA2A (0.44) | ADRB1ADRB2 | |
| SCHEMBL6259255 | 0.61 | ADRB2 (0.55) | ADRB1ADRB2 | |
| SCHEMBL6399196 | 0.60 | ADRB3 (0.45) | ADRB1ADRB2 | |
| SCHEMBL1053291 | 0.60 | TP53 (0.43) | MAPT | |
| SCHEMBL28766379 | 0.59 | HTR1A (0.46) | ALOX5MAPTKMT2A | |
| SCHEMBL1716142 | 0.59 | TAAR1 (0.52) | ADRB1ADRB2MEN1KMT2ATAAR1 | |
| SCHEMBL8702920 | 0.58 | TAAR1 (0.56) | MEN1MAPTKMT2ATAAR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551792-A1 | NOVEL BETA MIMETICS WITH EXTENDED DURATION OF ACTION, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004033412-A1 | NOVEL BETA MIMETICS WITH EXTENDED DURATION OF ACTION, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-04-22 | — | — | WO | disclosed |