SCHEMBL624545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL623894	0.89	RBP4 (0.51)	RBP4TSHRAHR
	SCHEMBL623147	0.85	ALDH1A1 (0.52)	ALDH1A1MAPTDRD2DRD3TSHR
	SCHEMBL624765	0.82	ALDH1A1 (0.50)	RBP4ALDH1A1MAPTDRD2DRD3
	SCHEMBL624639	0.81	DRD2 (0.51)	RBP4ALDH1A1MAPTDRD2TSHR
	SCHEMBL624189	0.79	TP53 (0.44)	ALDH1A1MAPTLMNAHTTKMT2A
	SCHEMBL624147	0.79	MAPK14 (0.48)	MAPTLMNAGAAHTT
	SCHEMBL624216	0.78	RAB9A (0.42)	RBP4ALDH1A1MAPTDRD2TSHR
	SCHEMBL623694	0.77	RAB9A (0.42)	ALDH1A1MAPTTSHRLMNAMEN1
	SCHEMBL620825	0.77	KDM4E (0.44)	ALDH1A1MAPTTSHRLMNAMEN1
	SCHEMBL623910	0.76	LMNA (0.42)	ALDH1A1TSHRLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.