Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025835 | 0.72 | HSP90AA1 (0.50) | ALDH1A1TSHRHSD17B10POLBHSP90AA1 | |
| SCHEMBL5143659 | 0.71 | HSP90AA1 (0.57) | ALDH1A1TSHRHSD17B10POLBHSP90AA1 | |
| SCHEMBL894920 | 0.69 | SIGMAR1 (1.00) | SIGMAR1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL10556615 | 0.69 | SIGMAR1 (0.72) | SIGMAR1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL28393 | 0.69 | SIGMAR1 (1.00) | SIGMAR1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL3257458 | 0.69 | SIGMAR1 (0.45) | SIGMAR1OPRD1HTR6HTR3EHTR3B | |
| SCHEMBL1189519 | 0.69 | ALDH1A1 (0.63) | SIGMAR1USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL15603464 | 0.69 | CA2 (0.35) | ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL10558570 | 0.68 | SIGMAR1 (0.70) | SIGMAR1USP2ALDH1A1TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL1597474 | 0.68 | SIGMAR1 (0.96) | SIGMAR1USP2ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542991-A1 | PYRIMIDINE COMPOUNDS AS THERAPEUTIC AGENTS | Euro-Celtique, S.A. (LU) | 2005-06-22 | — | — | EP | disclosed |
| US-20040127501-A1 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2004-07-01 | — | — | US | disclosed |
| WO-2004029044-A1 | PYRIMIDINE COMPOUNDS AS THERAPEUTIC AGENTS | EURO-CELTIQUE, S.A. (LU) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127501-A1 | Therapeutic agents useful for treating pain | CACNA1A, GRIN2A, HTT | SIGMAR1 329/4885USP2 4279/4885ALDH1A1 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.