Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796390 | 0.85 | IMPDH2 (0.61) | IMPDH2STAT3ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7672373 | 0.79 | CA1 (0.47) | CA1CA2IMPDH2STAT3ALDH1A1 | |
| SCHEMBL6222317 | 0.74 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL29696608 | 0.73 | ALDH1A1 (0.78) | STAT3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28454974 | 0.73 | ALDH1A1 (0.78) | STAT3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5463490 | 0.72 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL5462258 | 0.70 | ALDH1A1 (0.63) | STAT3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5452268 | 0.70 | ALDH1A1 (0.58) | STAT3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7545236 | 0.69 | LMNA (0.59) | ALDH1A1 | |
| SCHEMBL30747701 | 0.69 | LMNA (0.59) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100540551-C | Quinoline, its preparation method and medicinal use thereof | UNIV CHINA PHARMA (CN) | 2009-09-16 | — | — | CN | disclosed |
| CN-101012224-A | Quinoline derivative, preparation method and medical use thereof | UNIV CHINA PHARMA (CN) | 2007-08-08 | — | — | CN | disclosed |
| EP-1499594-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | Wyeth Holdings Corporation (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003093241-A1 | PROCESS FOR THE PREPARATION OF 7-SUBSTITUTED-3-QUINOLINE AND 3-QUINOL-4-ONE CARBONITRILES | WYETH HOLDINGS CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |
| CN-87100298-A | Improving one's methods of preparation quinoline-3-carboxylic acid antiseptic-germicide | — | 1987-08-19 | — | — | CN | disclosed |