SCHEMBL6253296

SCHEMBL6253296

Cc1cccc(C2=C(c3cccc4ccccc34)[Si](C)(C)C(c3cccc4ccccc34)=C2c2cccc(C)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
ENPP1 P22413 2/20 0.37
NR1I3 Q14994 2/20 0.37
RAB9A P51151 2/20 0.37
KMT2A Q03164 1/20 0.37
NPC1 O15118 1/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
CSNK1D P48730 1/20 0.36
CSNK1E P49674 1/20 0.36
MAPK14 Q16539 1/20 0.36
ENPP3 O14638 2/20 0.35
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
CYP2A6 P11509 2/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6258504 0.85 ALDH1A1 (0.42) ENPP1KMT2ACA12CA1CA2
SCHEMBL6252863 0.83 TSHR (0.42) RAB9AKMT2ANPC1ENPP3ALDH1A1
SCHEMBL6252120 0.81 CYP1A2 (0.39) NR1I3RAB9AKMT2ANPC1CSNK1D
SCHEMBL6255614 0.80 PTGS2 (0.38) MAOBRAB9AKMT2ANPC1CA12
SCHEMBL4323024 0.80 ENPP1 (0.48) MAOAMAOBENPP1NR1I3RAB9A
SCHEMBL6254099 0.80 MAPK14 (0.42) RAB9AKMT2ANPC1CSNK1DCSNK1E
SCHEMBL6254825 0.79 RAB9A (0.44) NR1I3RAB9AKMT2ANPC1ALDH1A1
SCHEMBL6256347 0.78 ACHE (0.44) RAB9AKMT2ANPC1ALDH1A1TSHR
SCHEMBL6257951 0.78 SMN1; SMN2 (0.51) RAB9AKMT2ANPC1ALDH1A1TSHR
SCHEMBL7122217 0.78 HTR7 (0.39) RAB9ANPC1ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 EP disclosed
EP-0754691-B1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORP (JP) 2003-11-19 EP disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 EP disclosed