SCHEMBL10038535

SCHEMBL10038535

C[Si]1(C)C(c2ccc(-c3ccccn3)nc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccc(-c2ccccn2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 4/20 0.50
KDM4E B2RXH2 5/20 0.42
LMNA P02545 4/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
P4HTM Q9NXG6 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
TP53 P04637 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
PKM P14618 3/20 0.42
RAB9A P51151 3/20 0.42
ALOX15 P16050 2/20 0.42
HTT P42858 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18016432 0.92 HPGDS (0.47) HPGDSKDM4ELMNACCR1CCR5
SCHEMBL17249482 0.91 CYP2A6 (0.57) HPGDSKDM4ETP53SMN1; SMN2PKM
SCHEMBL10018839 0.90 CYP2A6 (0.46) HPGDSKDM4ELMNACCR1CCR5
SCHEMBL12114839 0.88 HPGDS (0.48) HPGDSKDM4ELMNACCR1CCR5
SCHEMBL6254179 0.87 HPGDS (0.45) HPGDS
SCHEMBL7116753 0.84 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16189449 0.83 CCR1 (0.43) HPGDSCCR1CCR8CYP2A6TGFBR1
SCHEMBL28378194 0.82 HPGDS (0.45) HPGDSKDM4ELMNACCR1CCR5
SCHEMBL6252273 0.81 KDM4E (0.41) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16194539 0.81 RXFP1 (0.39) HPGDSKDM4ELMNACCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device Konica Minolta, Inc. (JP) 2019-11-05 US disclosed
US-10355236-B2 Transparent electrode and electronic device Konica Minolta, Inc. (JP) 2019-07-16 US disclosed
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2019-07-11 US disclosed
US-10347850-B2 Organic electroluminescent element, lighting device and display device Konica Minolta, Inc. (JP) 2019-07-09 US disclosed
US-9966557-B2 Translucent electrode, and electronic device Konica Minolta, Inc. (JP) 2018-05-08 US disclosed
US-9966557-B2 Translucent electrode, and electronic device Konica Minolta, Inc. (JP) 2018-05-08 US disclosed
US-9960356-B2 Organic electroluminescence device, lighting equipment and display device Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9960356-B2 Organic electroluminescence device, lighting equipment and display device Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9947889-B2 Transparent electrode, electronic device, and organic electroluminescent element KONICA MINOLTA INC. (JP) 2018-04-17 US disclosed
US-9947889-B2 Transparent electrode, electronic device, and organic electroluminescent element KONICA MINOLTA INC. (JP) 2018-04-17 US disclosed
US-20120326601-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-12-27 US disclosed
US-20120261654-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-10-18 US disclosed
US-20120193619-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND LIGHTING DEVICE USING SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2012-08-02 US disclosed
US-20120037889-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE AND ILLUMINATION DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2012-02-16 US disclosed
US-20120018714-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY APPARATUS, AND LIGHTING APPARATUS KONICA MINOLTA HOLDINGS, INC. (JP) 2012-01-26 US disclosed
US-20120007072-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MERCK PATENT GMBH (DE) 2012-01-12 US disclosed
US-20110272687-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, AND ILLUMINATION DEVICE AND DISPLAY DEVICE EACH COMPRISING THE ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-10 US disclosed
US-8053024-B2 Method for manufacturing organic electroluminescent device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-08 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20090081357-A1 METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10468610-B2 Isomer-mixture metal complex composition, organic electroluminescent element, illuminator, and display device EMC2, ELP1, EMC1 HPGDS 4805/4885KDM4E 1893/4885LMNA 3582/4885
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 HPGDS 4500/4885KDM4E 1253/4885LMNA 2374/4885
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL HPGDS 4564/4885KDM4E 367/4885LMNA 3272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.