Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273670 | 0.84 | GPR84 (0.68) | ALDH1A1RAB9ANR4A2KMT2AGPR84 | |
| SCHEMBL6238042 | 0.79 | LMNA (0.56) | ALDH1A1LMNARAB9ANR4A2KDM4E | |
| SCHEMBL9717042 | 0.77 | POLB (0.52) | ALDH1A1LMNARAB9AKMT2AKDM4E | |
| SCHEMBL31006022 | 0.76 | TSHR (0.52) | ALDH1A1LMNARAB9ANR4A2KMT2A | |
| SCHEMBL31406948 | 0.76 | KCNMA1 (0.56) | ALDH1A1LMNARAB9AKMT2AKDM4E | |
| SCHEMBL975117 | 0.74 | ALDH1A1 (0.68) | ALDH1A1RAB9AKMT2AKDM4E | |
| SCHEMBL31406949 | 0.74 | HTT (0.56) | ALDH1A1LMNARAB9APOLBHPGD | |
| SCHEMBL3976054 | 0.73 | NR4A2 (0.71) | ALDH1A1LMNARAB9ANR4A2KDM4E | |
| SCHEMBL7262531 | 0.72 | GAA (0.60) | ALDH1A1LMNARAB9AKMT2AKDM4E | |
| SCHEMBL6327424 | 0.72 | GPR84 (0.60) | ALDH1A1LMNARAB9ANR4A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000813-A1 | HETEROARYLAMINO-PHENYLKETONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-01-06 | — | — | WO | disclosed |