Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | CDK4 | P11802 | 2/20 | 0.47 |
| ▸ | CCND1 | P24385 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251507 | 0.82 | GPR84 (0.77) | NR4A2GPR84ALDH1A1KDRMAPT | |
| SCHEMBL6257685 | 0.79 | ALDH1A1 (0.53) | LMNARAB9ANR4A2HSD17B10KDM4E | |
| SCHEMBL8109983 | 0.77 | NR4A2 (0.67) | LMNARAB9ANR4A2HSD17B10KDM4E | |
| SCHEMBL3976054 | 0.77 | NR4A2 (0.71) | LMNARAB9ANR4A2HSD17B10KDM4E | |
| SCHEMBL6327424 | 0.76 | GPR84 (0.60) | LMNARAB9ANR4A2HSD17B10KDM4E | |
| SCHEMBL27811127 | 0.76 | HSD17B10 (0.79) | LMNARAB9ANR4A2HSD17B10KDM4E | |
| SCHEMBL3725153 | 0.75 | NR4A2 (0.63) | LMNARAB9ANR4A2HSD17B10KDM4E | |
| SCHEMBL11803848 | 0.74 | LMNA (0.71) | LMNARAB9ANR4A2HSD17B10KDM4E | |
| SCHEMBL5962865 | 0.74 | MAPT (0.51) | HSD17B10KDM4EALDH1A1HTTMAPT | |
| SCHEMBL9717019 | 0.74 | MAPK13 (0.55) | HSD17B10KDM4EALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000813-A1 | HETEROARYLAMINO-PHENYLKETONE DERIVATIVES AND THEIR USE AS KINASE INHIBITORS | IMCLONE SYSTEMS INCORPORATED (US) | 2005-01-06 | — | — | WO | disclosed |