Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704245 | 0.84 | L3MBTL1 (0.56) | CYP2C9FPR2L3MBTL1KDM4EGAA | |
| SCHEMBL29811285 | 0.83 | ALDH1A1 (0.57) | CYP2C9FPR2L3MBTL1KDM4EGAA | |
| SCHEMBL2632301 | 0.83 | ALDH1A1 (0.57) | CYP2C9FPR2L3MBTL1KDM4EGAA | |
| SCHEMBL19078878 | 0.81 | GABRP (0.56) | CYP2C9CYP2C19RECQLNAMPTHDAC1 | |
| SCHEMBL5012151 | 0.80 | FAAH (0.61) | CYP2C9L3MBTL1KDM4EGAAMAPT | |
| SCHEMBL27566380 | 0.80 | FPR2 (0.46) | CYP2C9FPR2L3MBTL1KDM4EGAA | |
| SCHEMBL20037838 | 0.79 | RECQL (0.58) | CYP2C9CYP2C19RECQLFPR2L3MBTL1 | |
| SCHEMBL8194183 | 0.79 | ALDH1A1 (0.49) | CYP2C9FPR2L3MBTL1KDM4EGAA | |
| SCHEMBL1697057 | 0.79 | L3MBTL1 (0.48) | CYP2C9FPR2L3MBTL1KDM4EGAA | |
| SCHEMBL19323949 | 0.79 | ALDH1A1 (0.53) | CYP2C9FPR2L3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020222-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | claimed |
| WO-2012020222-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |
| EP-0383091-B1 | Insecticidally active nitro compounds | BAYER AGROCHEM KK (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-5204359-A | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5084467-A | INSECTICIDALLY ACTIVE NITRO GUANIDINE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0383091-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-08-22 | — | — | EP | disclosed |