Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30057167 | 1.00 | PNMT (0.44) | PNMTACP3AOC3PDE1BOPRM1 | |
| SCHEMBL8897527 | 0.83 | HDAC4 (0.37) | ADRB1ALDH1A1HPGD | |
| SCHEMBL11462317 | 0.83 | AOC3 (0.44) | PNMTACP3AOC3PDE1BOPRM1 | |
| SCHEMBL1047528 | 0.82 | ACP3 (0.47) | PNMTACP3AOC3OPRM1OPRD1 | |
| SCHEMBL384041 | 0.81 | ACP3 (0.46) | PNMTACP3AOC3OPRM1OPRD1 | |
| SCHEMBL2601111 | 0.81 | PNMT (0.47) | PNMTACP3AOC3PDE1BOPRM1 | |
| SCHEMBL29428797 | 0.81 | PGR (0.47) | PNMTACP3AOC3OPRM1OPRD1 | |
| SCHEMBL17061793 | 0.81 | ACP3 (0.46) | PNMTACP3AOC3OPRM1OPRD1 | |
| SCHEMBL254476 | 0.81 | PGR (0.47) | PNMTACP3AOC3OPRM1OPRD1 | |
| SCHEMBL634062 | 0.79 | ADRB1 (0.42) | PNMTACP3AOC3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0076721-B1 | PROCESS FOR THE CARBONYLATION OF SECONDARY BENZYL HALIDES | Montedison S.p.A. (IT) | 1985-02-06 | — | — | EP | claimed |
| EP-0076721-A1 | Process for the carbonylation of secondary benzyl halides | Montedison S.p.A. (IT) | 1983-04-13 | — | — | EP | claimed |
| US-20260000642-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | TAY THERAPEUTICS LTD (GB) | 2026-01-01 | — | — | US | disclosed |
| US-20250263370-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | Tay Therapeutics Limited (GB) | 2025-08-21 | — | — | US | disclosed |
| EP-4561561-A2 | SUBSTITUTED 3,4-DIHYDROQUINOLINONE INHIBITORS OF TSHR | Septerna, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| EP-4558224-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | Tay Therapeutics Limited (GB) | 2025-05-28 | — | — | EP | disclosed |
| US-20250099478-A1 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-03-27 | — | — | US | disclosed |
| CN-115551839-B | Heteroaryl-triazole compounds as pesticides | 拜耳公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023146809-A9 | PLASMA KALLIKREIN INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024026076-A2 | SUBSTITUTED 3,4-DIHYDROQUINOLINONE INHIBITORS OF TSHR | SEPTERNA, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026076-A2 | SUBSTITUTED 3,4-DIHYDROQUINOLINONE INHIBITORS OF TSHR | SEPTERNA, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| EP-0754665-B1 | 3-substituted-alpha,beta-dibromoethylbenzene and process for preparing the same | MITSUBISHI CHEM CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5841004-A | 3-substituted-α, β-dibromoethylbenzene and process for preparing the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| EP-0754665-A2 | 3-substituted-alpha,beta-dibromoethylbenzene and process for preparing the same | Mitsubishi Chemical Corporation (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5026729-A | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1991-06-25 | — | — | US | disclosed |
| US-4633026-A | DEHYDROHALOGENATION OF RING-HALOGENATED ALPHA- OR BETA-BROMOETHYL BENZENES WITH STRONG BASE, POLYOXYETHYLENE GLYCOL CATALYST, AMINE POLYMERIZATION INHIBITOR | ETHYL CORPORATION (US) | 1986-12-30 | — | — | US | disclosed |
| EP-0076721-B1 | PROCESS FOR THE CARBONYLATION OF SECONDARY BENZYL HALIDES | Montedison S.p.A. (IT) | 1985-02-06 | — | — | EP | disclosed |
| EP-0076721-A1 | Process for the carbonylation of secondary benzyl halides | Montedison S.p.A. (IT) | 1983-04-13 | — | — | EP | disclosed |
| US-4210610-A | CHLOROARYLHYDROXY SUBSTITUTED ACETYLENES | GULF RESEARCH AND DEVELOPMENT COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260000642-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | BET1, BRD4, PHKB | PNMT 4171/4885ACP3 4389/4885AOC3 3250/4885 |
| US-20250263370-A1 | PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS | BET1, PHKB, BRD4 | PNMT 1734/4885ACP3 1389/4885AOC3 4605/4885 |
| US-20250099478-A1 | PLASMA KALLIKREIN INHIBITORS | KLKB1, SERPINE1, KLK5 | PNMT 4185/4885ACP3 3092/4885AOC3 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.