Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TACR3 | P29371 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453343 | 0.74 | HTR1A (0.71) | TSHRHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL29495713 | 0.74 | LMNA (0.65) | TSHRHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL6259088 | 0.74 | LMNA (0.65) | TSHRHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL94576 | 0.73 | SMN1; SMN2 (0.68) | TSHRHTTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1458090 | 0.72 | HTR1A (0.73) | TSHRALDH1A1SMN1; SMN2HTR1AHTR2A | |
| SCHEMBL5537738 | 0.72 | HTR1A (0.73) | ALDH1A1SMN1; SMN2HTR1AHTR2AHTR7 | |
| SCHEMBL8001697 | 0.72 | ALPL (0.54) | HTTALDH1A1SMN1; SMN2TACR3MAPT | |
| SCHEMBL17884901 | 0.72 | RAB9A (0.72) | HTTALDH1A1SMN1; SMN2HTR1AHTR2A | |
| SCHEMBL11100857 | 0.72 | ALDH1A1 (0.75) | HTTALDH1A1SMN1; SMN2LMNAHTR1A | |
| SCHEMBL6714846 | 0.72 | ALDH1A1 (0.75) | HTTALDH1A1SMN1; SMN2LMNAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590329-A1 | N-ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | Aventis Pharma S.A. (FR) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004078732-A1 | N-ARYL HETEROAROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2004-09-16 | — | — | WO | disclosed |