Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262193 | 1.00 | CA1 (0.55) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL26276881 | 0.95 | CA1 (0.50) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL9237969 | 0.87 | LPAR3 (0.47) | CYP3A4TSHRTP53 | |
| SCHEMBL3233444 | 0.82 | CA1 (0.75) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL9463259 | 0.80 | LTA4H (0.46) | — | |
| SCHEMBL18444075 | 0.80 | CES2 (0.59) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL30497663 | 0.80 | CA1 (0.67) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL18444211 | 0.80 | CES2 (0.59) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL4430882 | 0.80 | CES2 (0.67) | CA1CA2BCHEACHEALDH1A1 | |
| SCHEMBL3229969 | 0.80 | CA1 (0.58) | CA1CA2BCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043982-B1 | LIPASE INHIBITING POLYMERS | GENZYME CORP (US) | 2005-11-09 | — | — | EP | disclosed |
| US-20050085535-A1 | Lipase inhibiting polymers | GENZYME CORPORATION (US) | 2005-04-21 | — | — | US | disclosed |
| US-6875428-B2 | Lipase inhibiting polymers | GENZYME CORPORATION (US) | 2005-04-05 | — | — | US | disclosed |
| US-20030185789-A1 | Lipase inhibiting polymers | GELTEX PHARMACEUTICALS, INC. | 2003-10-02 | — | — | US | disclosed |
| US-6572850-B1 | Treating obesity by administering a polyether substituted with a pendant B-lactone group;reduction in fat hydrolysis and absorption | GELTEX PHARMACEUTICALS, INC. | 2003-06-03 | — | — | US | disclosed |
| US-6558657-B1 | Synthetic polymer, carbohydrate or protein substituted with disulfide moiety that inhibits fat hydrolysis | GELTEX PHARMACEUTICALS, INC. | 2003-05-06 | — | — | US | disclosed |
| US-6352692-B1 | POLYMERS WITH PHOSPHINO-CONTAINING FUNCTIONAL GROUP SUBSTITUENTS; ORALLY ADMINISTERING TO TREAT OBESITY AND HYPERTRIGLYCERIDEMIA | GELTEX PHARMACEUTICALS, INC. | 2002-03-05 | — | — | US | disclosed |
| US-6267952-B1 | ORALLY ADMINISTERING TO MAMMAL A MODIFIED POLYMER WHICH FOR TREATING OBESITY | GELTEX PHARMACEUTICALS, INC. | 2001-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030185789-A1 | Lipase inhibiting polymers | PNLIP, LIPC, LPL | CA1 4039/4885CA2 3350/4885BCHE 170/4885 |
| US-20050085535-A1 | Lipase inhibiting polymers | PNLIP, LIPC, LPL | CA1 4039/4885CA2 3350/4885BCHE 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.