SCHEMBL626457

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL625805	0.88	NR1I2 (0.54)	NR1I2HDAC6TRPV3SLC6A9PKLR
	SCHEMBL625816	0.78	TRPV3 (0.39)	HDAC6TRPV3PDK2HSD11B1
	SCHEMBL624825	0.78	NR1I2 (0.57)	NR1I2TRPV3SLC6A2SLC6A4PDE2A
	SCHEMBL14893962	0.77	NR1I2 (0.51)	NR1I2HDAC6TRPV3SLC6A9PKLR
	SCHEMBL14894480	0.76	NR1I2 (0.49)	NR1I2HDAC6TRPV3SLC6A9PKLR
	SCHEMBL624777	0.75	NR1I2 (0.43)	NR1I2HDAC6TRPV3SLC6A9PKLR
	SCHEMBL14893425	0.75	SLC6A9 (0.36)	NR1I2HDAC6SLC6A9PKLRBDKRB1
	SCHEMBL12473778	0.74	HSD11B1 (0.39)	NR1I2HDAC6SLC6A9PKLRBDKRB1
	SCHEMBL14893688	0.74	P2RX7 (0.36)	NR1I2HDAC6SLC6A9PKLRBDKRB1
	SCHEMBL12473827	0.72	HSD11B1 (0.38)	NR1I2HDAC6SLC6A9PKLRBDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.