Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625758 | 0.81 | REN (0.43) | CTSKACE | |
| SCHEMBL625757 | 0.81 | REN (0.43) | CTSKACE | |
| SCHEMBL626561 | 0.77 | SMN1; SMN2 (0.41) | CTSKGAATDP1SMN1; SMN2NPC1 | |
| SCHEMBL7288109 | 0.76 | ACE (0.54) | CTSKSIRT2ACEACE2CNR1 | |
| SCHEMBL7288116 | 0.76 | ACE (0.54) | CTSKSIRT2ACEACE2CNR1 | |
| SCHEMBL626560 | 0.74 | ALDH1A1 (0.41) | GAATDP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10082616 | 0.73 | IKBKB (0.41) | CTSKSIRT2GAARAB9ALMNA | |
| SCHEMBL7447301 | 0.73 | CTSK (0.44) | CTSKSIRT2TDP1SMN1; SMN2NPC1 | |
| SCHEMBL625898 | 0.72 | PPARA (0.48) | CTSKACEITGB3ITGA2B | |
| SCHEMBL5086307 | 0.72 | HDAC6 (0.49) | CTSKHPGDACEACE2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603491-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERIC FORMS OF 2,3-DIAMINOPROPIONIC ACID DERIVATIVES | SANOFI (FR) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012019967-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERIC FORMS OF 2,3-DIAMINOPROPIONIC ACID DERIVATIVES | SANOFI (FR) | 2012-02-16 | — | — | WO | disclosed |