Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626559 | 0.77 | CTSK (0.40) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL7447309 | 0.71 | CTSK (0.45) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL2052808 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL5086318 | 0.70 | FAAH (0.45) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL13506655 | 0.70 | NPSR1 (0.58) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL13387483 | 0.70 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL349655 | 0.69 | FAAH (0.52) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL9317172 | 0.69 | POLB (0.58) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL7357011 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL9848476 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603491-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERIC FORMS OF 2,3-DIAMINOPROPIONIC ACID DERIVATIVES | SANOFI (FR) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012019967-A1 | PROCESS FOR THE PREPARATION OF ENANTIOMERIC FORMS OF 2,3-DIAMINOPROPIONIC ACID DERIVATIVES | SANOFI (FR) | 2012-02-16 | — | — | WO | disclosed |