Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | TDP2 | O95551 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 3/20 | 0.33 |
| ▸ | CDC25C | P30307 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16416442 | 0.76 | IDO1 (0.40) | IDO1TDP2NSD2CDC25BPIN1 | |
| SCHEMBL6269145 | 0.70 | TDP2 (0.55) | IDO1TDP2NSD2CDC25BMAOA | |
| SCHEMBL1650480 | 0.70 | IDO1 (1.00) | IDO1CDC25BPIN1MAOAMAOB | |
| SCHEMBL12390669 | 0.65 | IDO1 (0.41) | IDO1CDC25BPIN1MAOAMAOB | |
| SCHEMBL2922398 | 0.64 | PDE10A (0.52) | ALDH1A1KDM4EHPGDMAPK1HSD17B10 | |
| SCHEMBL7830760 | 0.62 | ALDH1A1 (0.44) | IDO1CDC25BPIN1MAOAMAOB | |
| SCHEMBL7443013 | 0.61 | ALOX15 (0.48) | IDO1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL3958516 | 0.59 | IDO1 (0.44) | IDO1CDC25BPIN1MAOAMAOB | |
| Naphthoquinone SCHEMBL29354680 | 0.58 | IDO1 (1.00) | IDO1TDP2CDC25BPIN1MAOA | |
| SCHEMBL16736421 | 0.58 | CA12 (0.55) | ALDH1A1AOC3CA12CA1CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118903118-A | Use of 3-substituted naphtho [2,3-b ] isoxazole-4, 9-dione derivatives for anti-psoriasis | 中南大学 | 2024-11-08 | — | — | CN | disclosed |
| EP-1202993-B1 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LAFON LABOR (FR) | 2005-10-19 | — | — | EP | disclosed |
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | disclosed |
| US-6583150-B1 | Cytotoxic propertie; antitumor; pyrido-(3,2-g)quinoline-5,10-diones; benzo(b)pyrido(4,3,2-de)(1,7)-phenanthroline-8-ones | LABORATORIE L. LAFON (FR) | 2003-06-24 | — | — | US | disclosed |
| US-6515127-B1 | The invention concerns a method for preparing quinoline-5,8-diones of formula (I) light-induced oxygenation of a 8-hydroxyquinoline. and intermediates | LABORATOIRE L. LAFON (FR) | 2003-02-04 | — | — | US | disclosed |
| EP-1202993-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2002-05-08 | — | — | EP | disclosed |
| EP-1161432-A1 | PHARMACEUTICAL COMPOSITION BASED ON POLYAROMATIC COMPOUNDS | LABORATOIRE L. LAFON (FR) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001012632-A2 | PHENANTHROLINE-7-ONE DERIVATIVES AND THEIR THERAPEUTIC USES | LABORATOIRE L. LAFON (FR) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000055160-A1 | PHARMACEUTICAL COMPOSITION BASED ON POLYAROMATIC COMPOUNDS | LABORATOIRE L. LAFON (FR) | 2000-09-21 | — | — | WO | disclosed |