Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 17/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627055 | 0.83 | MAPT (0.48) | MAPTTHRBRXFP1GAALMNA | |
| SCHEMBL628000 | 0.82 | MAPT (0.42) | MAPTTHRBRXFP1GAALMNA | |
| SCHEMBL626841 | 0.74 | F2RL3 (0.33) | — | |
| SCHEMBL627222 | 0.74 | LMNA (0.39) | THRBRXFP1LMNATP53 | |
| SCHEMBL626887 | 0.73 | CKS1B (0.48) | MAPTTHRB | |
| SCHEMBL627088 | 0.72 | MAPT (0.32) | MAPTTHRB | |
| SCHEMBL627373 | 0.71 | MAP3K12 (0.46) | MAPTTHRB | |
| SCHEMBL628264 | 0.68 | BTK (0.51) | MAPTTHRB | |
| SCHEMBL22207215 | 0.67 | IDO1 (0.42) | HRH3 | |
| SCHEMBL3559247 | 0.64 | HRH3 (0.55) | MAPTLMNAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |