Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827924 | 0.84 | HTT (0.51) | HTTALOX5CYP1A2ARALDH1A1 | |
| SCHEMBL6271676 | 0.83 | TRPV1 (0.40) | CES2 | |
| SCHEMBL6269880 | 0.69 | IGF1R (0.38) | ALDH1A1 | |
| SCHEMBL6270872 | 0.68 | ALDH1A1 (0.46) | ALOX5ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL6274944 | 0.66 | ALOX5 (0.45) | ADRB1HTTALOX5CYP1A2ALDH1A1 | |
| SCHEMBL5906338 | 0.62 | NPBWR1 (0.41) | ADRB1HTTJUNNFKB1NFKB2 | |
| SCHEMBL2161149 | 0.62 | HTT (0.42) | ADRB1HTTJUNNFKB1NFKB2 | |
| SCHEMBL8730226 | 0.62 | CCR6 (0.48) | ADRB1JUNNFKB1NFKB2RELA | |
| SCHEMBL440959 | 0.62 | CES2 (0.58) | ADRB1CES2XPO1ALDH1A1 | |
| SCHEMBL22006511 | 0.61 | ADRB1 (0.44) | ADRB1JUNNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606271-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080984-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | WO | disclosed |