Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627389 | 1.00 | MME (0.52) | MMECTSSCTSKACECTSL | |
| SCHEMBL12661114 | 0.89 | CTSS (0.51) | MMECTSSCTSKCTSLSMN1; SMN2 | |
| SCHEMBL12661102 | 0.89 | CTSS (0.51) | MMECTSSCTSKCTSLSMN1; SMN2 | |
| SCHEMBL12256772 | 0.88 | TGM2 (0.48) | MMECTSSCTSKACECTSL | |
| SCHEMBL8305419 | 0.86 | PPARA (0.46) | MMEHTTALDH1A1TSHR | |
| SCHEMBL6401372 | 0.86 | ALDH1A1 (0.54) | SMN1; SMN2KMT2AHTTALDH1A1 | |
| SCHEMBL27349990 | 0.86 | ALDH1A1 (0.54) | SMN1; SMN2KMT2AHTTALDH1A1 | |
| SCHEMBL7406394 | 0.86 | FPR2 (0.48) | MMECTSSCTSKACECTSL | |
| SCHEMBL7406392 | 0.86 | FPR2 (0.48) | MMECTSSCTSKACECTSL | |
| SCHEMBL8315015 | 0.86 | ALDH1A1 (0.54) | SMN1; SMN2KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278922-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2016-03-08 | — | — | US | disclosed |
| EP-2419404-B1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC (US) | 2015-11-04 | — | — | EP | disclosed |
| CN-102459165-B | Antiviral compound | ABBVIE (US) | 2015-09-02 | — | — | CN | disclosed |
| CN-102459165-A | Anti-viral compounds | ABBOTT LAB | 2012-05-16 | — | — | CN | disclosed |
| EP-2419404-A1 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010120935-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2010-10-21 | — | — | WO | disclosed |
| US-20100267634-A1 | Anti-Viral Compounds | Abbott Labaoratories (US) | 2010-10-21 | — | — | US | disclosed |
| EP-0430459-B1 | Tetrahydronaphthalene derivatives and preparation thereof | TANABE SEIYAKU CO (JP) | 1994-06-22 | — | — | EP | disclosed |
| US-5206418-A | Thromboxan A2 antagonist | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5206428-A | Anticoagulants | TANABE SEIYAKU CO., LTD. (JP) | 1993-04-27 | — | — | US | disclosed |
| EP-0430459-A1 | Tetrahydronaphthalene derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267634-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | MME 131/4885CTSS 445/4885CTSK 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.