SCHEMBL628182

SCHEMBL628182

O=C(Cl)c1cccc(-c2ccccc2)c1C(=O)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.52
BCAT2 O15382 1/20 0.50
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CHRNB2 P17787 3/20 0.44
CHRNB4 P30926 3/20 0.44
CHRNA3 P32297 3/20 0.44
CHRNA4 P43681 3/20 0.44
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 1/20 0.44
FOLH1 Q04609 1/20 0.44
FABP3 P05413 1/20 0.43
FABP4 P15090 1/20 0.43
FABP5 Q01469 1/20 0.43
TSHR P16473 1/20 0.42
RECQL P46063 1/20 0.42
HTT P42858 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404978 1.00 HNF4A (0.52) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL29470845 0.94 HNF4A (0.50) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL7343199 0.84 FOLH1 (0.46) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL229441 0.84 BCAT2 (0.63) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL31636780 0.83 SLC6A3 (0.56) KMT2AMEN1SMN1; SMN2ALDH1A1ALOX15
SCHEMBL997944 0.81 HNF4A (0.56) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL9712509 0.81 HNF4A (0.52) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL28874983 0.80 ALDH1A1 (0.38) HNF4ABCAT2ALDH1A1ALOX15FOLH1
SCHEMBL3297211 0.80 BCAT2 (0.53) HNF4ABCAT2KMT2AMEN1SMN1; SMN2
SCHEMBL18825620 0.80 BCAT2 (0.59) HNF4ABCAT2KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 955 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080343-A Method for synthesizing polyarylketone compound 2026-05-26 CN claimed
CN-122080606-A Allyl polyarylester modified bismaleimide resin and preparation method and application thereof 2026-05-26 CN claimed
CN-122080404-A Copolyamide imide, film, preparation method and electronic device 2026-05-26 CN claimed
US-20260054227-A1 COMPOSITE MEMBRANE AND METHOD OF MAKING THE SAME H2MO TECH PTE LTD (SG) 2026-02-26 US claimed
US-12485388-B2 Composite membrane and method of making the same H2MO TECHNOLOGY PTE LTD (SG) 2025-12-02 US claimed
EP-4615204-A1 OPTICAL FILM HAVING EXCELLENT CRUSH RESISTANCE AND DISPLAY DEVICE COMPRISING SAME Kolon Industries, Inc. (KR) 2025-09-10 EP claimed
CN-120129850-A Optical film and display device including the same 可隆工业株式会社 2025-06-10 CN claimed
CN-120005178-A Method for producing polyamide polymer, polyamide nanoparticle, method for producing reverse osmosis membrane, and reverse osmosis membrane produced by using same 沃顿科技股份有限公司 2025-05-16 CN claimed
CN-119746656-A Preparation method of positively charged nanofiltration membrane, nanofiltration membrane and application of nanofiltration membrane 东莞市创明电池技术有限公司 2025-04-04 CN claimed
CN-119565382-A Method for cleaning reverse osmosis membrane and reverse osmosis membrane prepared by same 万华化学集团股份有限公司 2025-03-07 CN claimed
CN-111254506-A High-strength chitosan filament and interfacial photopolymerization preparation method and device thereof 武汉纺织大学 2020-06-09 CN claimed
CN-107486041-B Ultra-low pressure composite reverse osmosis membrane and preparation method thereof 常州市美纤膜技术有限公司 2020-04-28 CN claimed
CN-108452684-B Metal organic framework reverse osmosis membrane and preparation method thereof 时代沃顿科技有限公司 2020-04-24 CN claimed
US-20190263095-A1 PLASTIC LAMINATED FILM LG CHEM, LTD. (KR) 2019-08-29 US claimed
EP-3466680-A1 PLASTIC LAMINATE FILM LG Chem, Ltd. (KR) 2019-04-10 EP claimed
US-20160263530-A1 FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) 2016-09-15 US claimed
EP-1020218-B1 COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME NITTO DENKO CORP (JP) 2003-05-21 EP claimed
EP-1020218-A1 COMPOSITE REVERSE OSMOSIS MEMBRANE AND PROCESS FOR PREPARING THE SAME NITTO DENKO CORPORATION (JP) 2000-07-19 EP claimed
EP-0517943-A1 Copolyestercarbonate polymers derived from diaryl dicarboxylic acids and their derivatives and blends thereof THE DOW CHEMICAL COMPANY (US) 1992-12-16 EP claimed
US-5045610-A Thermoplastic Molding Materials THE DOW CHEMICAL COMPANY (US) 1991-09-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260054227-A1 COMPOSITE MEMBRANE AND METHOD OF MAKING THE SAME AQP1, AQP4, AQP3 HNF4A 2789/4885BCAT2 3924/4885KMT2A 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.