Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 11/20 | 0.34 |
| ▸ | THRB | P10828 | 6/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839415 | 0.80 | PGK1 (0.33) | PPARGRORC | |
| SCHEMBL7674938 | 0.80 | PPOX (0.44) | — | |
| SCHEMBL6278159 | 0.77 | RORC (0.37) | TGFBR1THRBHPGDCSNK1DPPARG | |
| SCHEMBL7675340 | 0.76 | PPOX (0.32) | PPARGRORC | |
| SCHEMBL7669291 | 0.73 | HPGD (0.38) | HPGDPPARGRORC | |
| SCHEMBL8895167 | 0.72 | SIGMAR1 (0.42) | TGFBR1THRBMAPK14PPARGRORC | |
| SCHEMBL7674234 | 0.70 | KDM4E (0.39) | ALDH1A1HPGD | |
| SCHEMBL7675811 | 0.70 | PGK1 (0.32) | PPARGRORC | |
| SCHEMBL6279839 | 0.69 | ALOX5AP (0.32) | ALDH1A1HPGD | |
| SCHEMBL6671518 | 0.68 | ALOX5AP (0.32) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927193-B2 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-09 | — | — | US | disclosed |
| US-20040267014-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-12-30 | — | — | US | disclosed |
| EP-1432692-A1 | ARYL ETHER DERIVATIVES AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-20030195118-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. | 2003-10-16 | — | — | US | disclosed |
| US-6613718-B2 | 2,3-Dihydro-2-thioxo-pyrimidinone derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| US-20030130122-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. | 2003-07-10 | — | — | US | disclosed |
| WO-2003029225-A1 | ARYL ETHER DERIVATIVES AND PROCESSES FOR THEIR PREPARATION AND HERBICIDAL AND DESICCANT COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130122-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | CBR3, CBR1, DDT | TGFBR1 4124/4885THRB 2828/4885MAPK14 3914/4885 |
| US-20030195118-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | CBR3, CBR1, DDT | TGFBR1 4126/4885THRB 2819/4885MAPK14 3897/4885 |
| US-20040267014-A1 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | CBR3, HDHD5, DDT | TGFBR1 3693/4885THRB 2604/4885MAPK14 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.