Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | MELK | Q14680 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674234 | 0.85 | KDM4E (0.39) | HPGDPOLBSMN1; SMN2 | |
| SCHEMBL6278159 | 0.82 | RORC (0.37) | HPGDRORCPPARGPDE4APDE4B | |
| SCHEMBL8895167 | 0.74 | SIGMAR1 (0.42) | RORCPPARGPDE4APDE4BPDE4C | |
| SCHEMBL6283083 | 0.73 | TGFBR1 (0.34) | HPGDRORCPPARG | |
| SCHEMBL7675340 | 0.72 | PPOX (0.32) | RORCPPARG | |
| SCHEMBL7674938 | 0.72 | PPOX (0.44) | — | |
| SCHEMBL6839415 | 0.72 | PGK1 (0.33) | RORCPPARG | |
| SCHEMBL9385152 | 0.68 | EGFR (0.34) | — | |
| SCHEMBL9287102 | 0.68 | MAPK1 (0.33) | — | |
| SCHEMBL8432458 | 0.67 | MAPK1 (0.34) | HPGDPOLBTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358885-B1 | PREEMERGENT OR POSTEMERGENT HERBICIDES OR PLANT GROWTH REGULANTS | MISSISSIPPI STATE UNIVERSITY | 2002-03-19 | — | — | US | disclosed |
| US-5977028-A | Substituted phenylheterocyclic herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0626962-B1 | SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES | DU PONT (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5670455-A | Substituted phenylheterocyclic herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0626962-A1 | SUBSTITUTED PHENYLHETEROCYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-07 | — | — | EP | disclosed |