Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284012 | 0.72 | TSHR (0.64) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL3857975 | 0.67 | ALDH1A1 (0.60) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL27553288 | 0.66 | ALDH1A1 (0.58) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL14397435 | 0.66 | NPSR1 (0.49) | L3MBTL1MAPK10RORBRORCNPSR1 | |
| SCHEMBL9851131 | 0.65 | G6PD (0.65) | ALDH1A1TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL6034332 | 0.65 | BCAT2 (0.46) | KMT2AMAPK10RORBRORCPTPN1 | |
| SCHEMBL15546044 | 0.64 | ALDH1A1 (0.44) | ALDH1A1TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL28417865 | 0.64 | KMT2A (0.45) | ALDH1A1TSHRL3MBTL1KMT2AMEN1 | |
| SCHEMBL16448326 | 0.64 | ALDH1A1 (0.55) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL6395918 | 0.64 | ALDH1A1 (0.50) | ALDH1A1TSHRL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |