Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19476106 | 0.78 | TSHR (1.00) | TSHRHSD17B10MAPK1KDM4EKMT2A | |
| SCHEMBL15528812 | 0.74 | MAPK1 (0.71) | TSHRHSD17B10MAPK1KDM4EKMT2A | |
| SCHEMBL6635707 | 0.73 | SMN1; SMN2 (0.69) | TSHRMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL6284014 | 0.72 | ALDH1A1 (0.42) | TSHRHSD17B10MAPK1KDM4EKMT2A | |
| SCHEMBL16425581 | 0.71 | PTPN1 (0.61) | TSHRKDM4EKMT2AMAPTTDP1 | |
| SCHEMBL6282860 | 0.70 | PTPN1 (0.72) | TSHR | |
| SCHEMBL30117825 | 0.69 | RAB9A (0.74) | TSHRHSD17B10MAPK1KDM4EKMT2A | |
| SCHEMBL6633552 | 0.69 | SMN1; SMN2 (1.00) | TSHRMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL30587183 | 0.69 | SMN1; SMN2 (1.00) | TSHRMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL1520253 | 0.69 | KMT2A (0.67) | TSHRHSD17B10MAPK1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |