Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26290273 | 0.83 | AMY1A (0.83) | AMY1AESR1ESR2TP53TDP1 | |
| SCHEMBL30485785 | 0.82 | ESR1 (0.68) | AMY1AESR1ESR2TP53TDP1 | |
| SCHEMBL1176702 | 0.82 | ESR1 (0.68) | AMY1AESR1ESR2TP53TDP1 | |
| SCHEMBL6573238 | 0.82 | ALOX15 (0.58) | AMY1AESR1ESR2TP53TDP1 | |
| SCHEMBL31294095 | 0.81 | AMY1A (0.68) | AMY1AESR1ESR2TP53TDP1 | |
| SCHEMBL7566966 | 0.80 | ESR1 (0.48) | ESR1ESR2TP53TDP1MAPT | |
| SCHEMBL15248109 | 0.80 | AMY1A (0.67) | AMY1AESR1ESR2MAPTTRPA1 | |
| SCHEMBL10789460 | 0.80 | AMY1A (0.53) | AMY1ATP53TDP1MAPTSMN1; SMN2 | |
| SCHEMBL4624112 | 0.79 | PYCR1 (0.42) | TP53TDP1SMN1; SMN2CYP3A4IDO1 | |
| SCHEMBL50622 | 0.79 | AMY1A (0.83) | AMY1AESR1ESR2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864381-B2 | Process for preparing acyloxybenzenesulfonates | CLARIANT GMBH (DE) | 2005-03-08 | — | — | US | disclosed |
| US-20040198995-A1 | Process for preparing acyloxybenzenesulfonates | CLARIANT GMBH | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198995-A1 | Process for preparing acyloxybenzenesulfonates | TST, TYR, ACMSD | AMY1A 2764/4885ESR1 2197/4885ESR2 3288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.