Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | EP300 | Q09472 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287087 | 0.88 | APP (0.33) | TLR8EP300POLBS100BBACE1 | |
| SCHEMBL6287315 | 0.88 | APP (0.33) | TLR8EP300POLBS100BBACE1 | |
| SCHEMBL6747642 | 0.88 | TLR8 (0.32) | TLR8POLB | |
| SCHEMBL6290903 | 0.86 | ALDH1A1 (0.44) | CA2S100BALDH1A1CYP3A4 | |
| SCHEMBL7043243 | 0.80 | POLB (0.33) | EP300POLBS100B | |
| SCHEMBL8067053 | 0.79 | TLR8 (0.38) | TLR8EP300POLBS100BNPSR1 | |
| SCHEMBL6290905 | 0.77 | ALDH1A1 (0.38) | S100BALDH1A1CYP3A4 | |
| SCHEMBL8927925 | 0.76 | TLR8 (0.35) | TLR8EP300POLBS100BNPSR1 | |
| SCHEMBL7763544 | 0.74 | TDP1 (0.47) | CA2NPSR1ALDH1A1CYP3A4 | |
| SCHEMBL6470613 | 0.73 | S100B (0.62) | CA2S100BNPSR1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | LANG GERARD (FR) | 2004-05-13 | — | — | US | claimed |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-09-11 | — | — | US | claimed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | claimed |
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | disclosed |
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | LANG GERARD (FR) | 2004-05-13 | — | — | US | disclosed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | KRT18, CDC73, DAO | TLR8 3493/4885CA2 2164/4885EP300 2550/4885 |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, NDUFB5, NDUFB4 | TLR8 3523/4885CA2 1713/4885EP300 2083/4885 |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, COXFA4L2 | TLR8 4482/4885CA2 1746/4885EP300 2799/4885 |
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, OAT, ACOX1 | TLR8 1812/4885CA2 2298/4885EP300 1480/4885 |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, NDUFB5 | TLR8 4396/4885CA2 2104/4885EP300 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.