Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 9/20 | 0.63 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20601786 | 1.00 | MMP9 (0.64) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL628640 | 1.00 | MMP9 (0.64) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL3856155 | 0.91 | MMP2 (0.73) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL19450360 | 0.90 | MMP2 (0.67) | MMP9MMP2ADAMTS4ALDH1A1ADAMTS5 | |
| SCHEMBL433897 | 0.90 | MMP2 (0.71) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL561565 | 0.90 | MMP2 (0.71) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| Chloromethane SCHEMBL7649372 | 0.89 | MMP2 (0.75) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL697477 | 0.89 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL697476 | 0.89 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4ALDH1A1 | |
| SCHEMBL1203540 | 0.89 | MMP2 (0.79) | MMP9TDP1MMP2ADAMTS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115248272-B | Method for detecting alpha-ketoglutaric acid and chiral 2-hydroxyglutaric acid | 深圳深检集团医学检验实验室 | 2023-04-18 | — | — | CN | claimed |
| CN-115248272-A | Method for detecting alpha-ketoglutaric acid and chiral 2-hydroxyglutaric acid | 深检集团(深圳)医学检验实验室 | 2022-10-28 | — | — | CN | claimed |
| JP-58154564-A | — | — | None | — | — | JP | disclosed |
| CN-120025312-A | Benzazepine derivatives | 大塚制药株式会社 | 2025-05-23 | — | — | CN | disclosed |
| US-20250051310-A1 | BENZAZEPINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-02-13 | — | — | US | disclosed |
| EP-4056557-B1 | BENZAZEPINE DERIVATIVES USEFUL AS MEDICAMENTS | OTSUKA PHARMA CO LTD (JP) | 2023-11-22 | — | — | EP | disclosed |
| US-20230265073-A1 | BENZAZEPINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-08-24 | — | — | US | disclosed |
| US-11673878-B2 | Benzazepine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-06-13 | — | — | US | disclosed |
| CN-115248272-B | Method for detecting alpha-ketoglutaric acid and chiral 2-hydroxyglutaric acid | 深圳深检集团医学检验实验室 | 2023-04-18 | — | — | CN | disclosed |
| CN-115248272-A | Method for detecting alpha-ketoglutaric acid and chiral 2-hydroxyglutaric acid | 深检集团(深圳)医学检验实验室 | 2022-10-28 | — | — | CN | disclosed |
| US-20210078976-A1 | BENZAZEPINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-03-18 | — | — | US | disclosed |
| US-6066739-A | Process for producing optically active imidazole compounds, intermediates for synthesizing the same, and process for producing the same | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-0972768-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE IMIDAZOLE COMPOUNDS, INTERMEDIATES FOR SYNTHESIZING THE SAME, AND PROCESS FOR PRODUCING THE SAME | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5942387-A | Combinatorial process for preparing substituted thiophene libraries | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0825164-A2 | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |
| US-5520725-A | Dental glass ionomer cement composition | GC CORPORATION (JP) | 1996-05-28 | — | — | US | disclosed |
| US-5281721-A | Substituted carboxy- or carbonyl sulfide-containing 2-benzopyran or 2-benzothiopyran derivatives | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |
| US-5109018-A | Emphysema therapy | GEORGIA TECH RESEARCH CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| US-4596822-A | Chromene or thiochromene ring containing enzyme inhibitor | GEORGIA TECH RESEARCH CORPORATION (US) | 1986-06-24 | — | — | US | disclosed |
| JP-S58154564-A | 1,3-DIZOLE DERIVATIVE | MITSUBISHI CHEM IND LTD | 1983-09-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210078976-A1 | BENZAZEPINE DERIVATIVES | AVPR2, AVPR1A, AVPR1B | MMP9 1806/4885TDP1 4462/4885MMP2 1796/4885 |
| US-20230265073-A1 | BENZAZEPINE DERIVATIVES | AVPR2, AVPR1A, AVPR1B | MMP9 1806/4885TDP1 4462/4885MMP2 1796/4885 |
| US-11673878-B2 | Benzazepine derivatives | AVPR2, AVPR1A, AVPR1B | MMP9 1806/4885TDP1 4462/4885MMP2 1796/4885 |
| US-20250051310-A1 | BENZAZEPINE DERIVATIVES | AVPR2, AVPR1A, AVPR1B | MMP9 1475/4885TDP1 4429/4885MMP2 1535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.