SCHEMBL6287101

SCHEMBL6287101

NCCCCCc1cc(F)cc(F)c1F

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MPO P05164 5/20 0.45
SLC6A4 P31645 3/20 0.37
RIPK1 Q13546 3/20 0.36
HRH1 P35367 2/20 0.34
MAOA P21397 1/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A3 Q01959 2/20 0.33
NOS1 P29475 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13692276 0.83 TAAR1 (0.43) MPORIPK1NOS1
SCHEMBL6283815 0.79 MPO (0.41) MPOSLC6A4HRH1MAOANOS1
SCHEMBL585543 0.78 CA2 (0.41) RIPK1NOS1
SCHEMBL12474329 0.78 RIPK1 (0.37) RIPK1NOS1
SCHEMBL855027 0.76 RIPK1 (0.41) MPORIPK1
SCHEMBL8438911 0.76 MPO (0.57) MPOSLC6A4
SCHEMBL17365375 0.74 MPO (0.38) MPOSLC6A4MAOANOS1
SCHEMBL25143184 0.73 MPO (0.56) MPOSLC6A4MAOASLC6A2SLC6A3
SCHEMBL6233798 0.72 HRH1 (0.47) MPOHRH1MAOA
SCHEMBL17552681 0.72 RIPK1 (0.39) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919291-B2 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-19 US disclosed
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization FZD7, FOS, COG4 MPO 496/4885SLC6A4 1434/4885RIPK1 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.