Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 11/20 | 0.38 |
| ▸ | PPARA | Q07869 | 11/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462241 | 0.82 | HDAC6 (0.37) | RARBRARGPPARGPPARAHDAC6 | |
| SCHEMBL6290939 | 0.80 | RARB (0.37) | RARBRARGPPARGPPARAHDAC6 | |
| SCHEMBL7120843 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1APPHTR1AMEN1 | |
| SCHEMBL6285804 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1APPHTR1AMEN1 | |
| SCHEMBL7117945 | 0.76 | HDAC6 (0.37) | RARBRARGPPARGPPARAHDAC6 | |
| SCHEMBL6290425 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1APPHTR1AMEN1 | |
| SCHEMBL6287388 | 0.72 | HDAC1 (0.36) | KDM4EALDH1A1HDAC6HDAC1APP | |
| SCHEMBL17525535 | 0.72 | NOS3 (0.36) | KDM4EALDH1A1APPHTR1AMEN1 | |
| SCHEMBL14507878 | 0.69 | RARB (0.38) | RARBRARGKDM4EALDH1A1HDAC6 | |
| SCHEMBL6287866 | 0.68 | KDM4E (0.34) | KDM4EALDH1A1APPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | LANG GERARD (FR) | 2004-05-13 | — | — | US | claimed |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-09-11 | — | — | US | claimed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | claimed |
| US-6890362-B2 | Oxidation dyeing composition for keratinous fibers and dyeing method using same | L'OREAL, S.A. (FR) | 2005-05-10 | — | — | US | disclosed |
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | LANG GERARD (FR) | 2004-05-13 | — | — | US | disclosed |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-09-11 | — | — | US | disclosed |
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-01-16 | — | — | US | disclosed |
| EP-1263398-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-12-11 | — | — | EP | disclosed |
| EP-1263399-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-12-11 | — | — | EP | disclosed |
| EP-1181004-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | disclosed |
| EP-1181005-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-2001066070-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066072-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066069-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001066071-A1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME | L'OREAL (FR) | 2001-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159221-A1 | Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent | KRT18, CDC73, DAO | RARB 266/4885RARG 385/4885PPARG 3049/4885 |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, NDUFB5, NDUFB4 | RARB 1257/4885RARG 1720/4885PPARG 3067/4885 |
| US-20030167579-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, COXFA4L2 | RARB 726/4885RARG 1014/4885PPARG 3964/4885 |
| US-20040088798-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, OAT, ACOX1 | RARB 1213/4885RARG 1335/4885PPARG 2459/4885 |
| US-20030009835-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, PPOX, NDUFB5 | RARB 846/4885RARG 1173/4885PPARG 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.