SCHEMBL629553

SCHEMBL629553

C=COC(Br)[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 4/20 0.45
▸ SLC28A1 O00337 1/20 0.37
▸ SLC28A2 O43868 1/20 0.37
▸ SLC29A1 Q99808 1/20 0.37
▸ SLC28A3 Q9HAS3 1/20 0.37
▸ P2RY2 P41231 8/20 0.36
▸ P2RY6 Q15077 3/20 0.36
▸ P2RY4 P51582 4/20 0.35
▸ TK1 P04183 2/20 0.35
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ PMP22 Q01453 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082848 0.88 DUT (0.37) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1009599 0.87 DUT (0.45) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL6035974 0.87 DUT (0.47) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL3072374 0.87 DUT (0.37) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL15414026 0.85 DUT (0.46) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL7394361 0.85 DUT (0.42) DUTP2RY2P2RY6P2RY4
SCHEMBL986334 0.83 DUT (0.52) DUTP2RY2P2RY6P2RY4
SCHEMBL3340603 0.83 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL4201158 0.83 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL2557435 0.83 DUT (0.50) DUTSLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 666 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250367301-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT INTEROLIGO CORPORATION (KR) 2025-12-04 — — US claimed
US-12448624-B2 Modified nucleic acid having improved treatment efficacy, and anticancer pharmaceutical composition containing same INTEROLIGO CORPORATION (KR) 2025-10-21 — — US claimed
CN-112888700-B Modified nucleic acid having improved therapeutic efficacy and anticancer pharmaceutical composition containing the same 因特欧力多公司 2025-03-04 — — CN claimed
US-20250049927-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF INTEROLIGO CORPORATION. (KR) 2025-02-13 — — US claimed
EP-4450092-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF Interoligo Corporation (KR) 2024-10-23 — — EP claimed
US-20240270780-A1 PROTEOLYSIS TARGETING COMPOUND WITH TISSUE TARGETING CAPABILITY AND USE THEREOF TAI BI DI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) 2024-08-15 — — US claimed
CN-118382461-A Modified oligonucleotide-drug conjugates and uses thereof 因特欧力多公司 2024-07-23 — — CN claimed
EP-4382134-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT Interoligo Corporation. (KR) 2024-06-12 — — EP claimed
CN-117835987-A Pharmaceutical composition for preventing or treating triple negative breast cancer containing oligonucleotide as active ingredient 因特欧力多公司 2024-04-05 — — CN claimed
WO-2023113243-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF 인터올리고 주식회사 2023-06-22 — — WO claimed
CN-1082894-A The anti-viral pharmaceutical compositions of vagina administration L C PHARCHEM LTD (CY) 1994-03-02 — — CN claimed
WO-1993023094-A1 USE OF HYDROGELS TO FIX BONE REPLACEMENTS M.U.R.S.T., ITALIAN MINISTRY FOR UNIVERSITIES AND SCIENTIFIC AND TECHNOLOGICAL RESEARCH (IT) 1993-11-25 — — WO claimed
WO-1993018763-A1 COMPOSITIONS OF N-(PHOSPHONOACETYL)-L-ASPARTIC ACID AND METHODS OF THEIR USE AS BROAD SPECTRUM ANTIVIRALS U.S. BIOSCIENCE, INC. (US) 1993-09-30 — — WO claimed
WO-1993002662-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITIONS FOR VAGINAL ADMINISTRATION L.C. PHARCHEM LTD. (CY) 1993-02-18 — — WO claimed
EP-0226029-B1 THYMIDINE KINASE DELETION MUTANTS OF BOVINE HERPESVIRUS-1, VACCINES AGAINST INFECTIOUS BOVINE RHINOTRACHEITIS CONTAINING SAME AND METHODS FOR THE PRODUCTION AND USE OF THE SAME NOVAGENE, INC. (US) 1992-03-11 — — EP claimed
US-4902678-A SYNERGISTIC MIXTURE; HERPES VIRUS INFECTIONS SYNTEX (U.S.A.) INC. (US) 1990-02-20 — — US claimed
EP-0101441-B1 ANTI-VIRAL COMPOSITIONS SYNTEX (U.S.A.) INC. (US) 1987-01-14 — — EP claimed
EP-0101441-A4 ANTI-VIRAL COMPOSITIONS. ENS BIO LOGICALS INC (CA) 1985-04-11 — — EP claimed
EP-0101441-A1 ANTI-VIRAL COMPOSITIONS. ENS BIO LOGICALS INC (CA) 1984-02-29 — — EP claimed
WO-1983002723-A1 ANTI-VIRAL COMPOSITIONS SMITH, KENDALL, O. 1983-08-18 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240270780-A1 PROTEOLYSIS TARGETING COMPOUND WITH TISSUE TARGETING CAPABILITY AND USE THEREOF ASGR1, ADRM1, PSMB11 DUT 3747/4885SLC28A1 3255/4885SLC28A2 3237/4885
US-20250367301-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRIPLE-NEGATIVE BREAST CANCER, COMPRISING OLIGONUCLEOTIDE AS ACTIVE INGREDIENT BRCA1, POLN, POLRMT DUT 46/4885SLC28A1 853/4885SLC28A2 1003/4885
US-20250049927-A1 MODIFIED OLIGONUCLEOTIDE-DRUG CONJUGATE AND USE THEREOF DCLRE1B, DUT, DCTD DUT 2/4885SLC28A1 224/4885SLC28A2 247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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