Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860669 | 0.79 | ALDH1A1 (0.57) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL2820858 | 0.78 | CA12 (0.49) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL11655146 | 0.77 | AGTR1 (0.64) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL3895943 | 0.77 | AGTR1 (0.64) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL28443830 | 0.74 | HSD11B1 (0.57) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL6544697 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL17548058 | 0.74 | IDO1 (0.44) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL5559803 | 0.74 | ALDH1A1 (0.64) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL2820495 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CA2CA12CA9SMN1; SMN2 | |
| SCHEMBL4579124 | 0.74 | NOS1 (0.52) | ALDH1A1CA2CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933390-B2 | Process for the arylation of aza-heterocycles with activated aromatics in presence of caesium carbonate | WARNER-LAMBERT COMPANY (US) | 2005-08-23 | — | — | US | disclosed |
| US-20040249185-A1 | Process for the arylation of aza-heterocycles with activated aromatics in presence of caesium carbonate | BARTH HUBERT (DE) | 2004-12-09 | — | — | US | disclosed |
| US-6774242-B1 | REACTING WITH INDOLE IN APROTIC SOLVENT | GOEDECKE GMBH (DE) | 2004-08-10 | — | — | US | disclosed |
| EP-1165512-A2 | METHOD FOR ARYLATING AZA-HETEROCYCLES WITH ACTIVATED AROMATIC COMPOUNDS IN THE PRESENCE OF CESIUM CARBONATE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059883-A2 | METHOD FOR PRODUCING N-ARYL-AZA-HETEROCYCLES IN THE PRESENCE OF CESIUM CARBONATE | Gödecke GmbH (DE) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249185-A1 | Process for the arylation of aza-heterocycles with activated aromatics in presence of caesium carbonate | AZI2, KCNH1, CA7 | ALDH1A1 1184/4885CA2 65/4885CA12 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.